Identification | Back Directory | [Name]
N2-iso-Butyroyl-3'-deoxy-3'-fluoro guanosine | [CAS]
2080404-20-0 | [Synonyms]
N2-iso-Butyroyl-3'-deoxy-3'-fluoro guanosine Guanosine, 3'-deoxy-3'-fluoro-N-(2-methyl-1-oxopropyl)- N-[9-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide | [Molecular Formula]
C14H18FN5O5 | [MOL File]
2080404-20-0.mol | [Molecular Weight]
355.32 |
Hazard Information | Back Directory | [Uses]
N2-iso-Butyroyl-3’-deoxy-3’-fluoro guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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