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2080404-20-0

2080404-20-0 Structure

2080404-20-0 Structure
IdentificationBack Directory
[Name]

N2-iso-Butyroyl-3'-deoxy-3'-fluoro guanosine
[CAS]

2080404-20-0
[Synonyms]

N2-iso-Butyroyl-3'-deoxy-3'-fluoro guanosine
Guanosine, 3'-deoxy-3'-fluoro-N-(2-methyl-1-oxopropyl)-
N-[9-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
[Molecular Formula]

C14H18FN5O5
[MOL File]

2080404-20-0.mol
[Molecular Weight]

355.32
Chemical PropertiesBack Directory
[density ]

1.78±0.1 g/cm3(Predicted)
[pka]

8.68±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

N2-iso-Butyroyl-3’-deoxy-3’-fluoro guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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