| Identification | Back Directory | [Name]
Hosenkoside K | [CAS]
160896-49-1 | [Synonyms]
Hosenkoside K
Hosenkoside K USP/EP/BP
Hosenkoside K, 98%, from Knoria valerianoides Thorelet Pitard
β-D-Glucopyranoside, (1R,2S,4aR,4bR,6'S,6aR,7R,8S,10aR,10bR,12aS)-7-[(β-D-glucopyranosyloxy)methyl]-6'-[(1S)-2-(β-D-glucopyranosyloxy)-1-methylethyl]octadecahydro-1-hydroxy-4a,4b,7,10a-tetramethylspiro[chrysene-2(1H),3'(4'H)-[2H]pyran]-8-yl 2-O-β-D-glucopyranosyl- | [Molecular Formula]
C54H92O25 | [MDL Number]
MFCD11111359 | [MOL File]
160896-49-1.mol | [Molecular Weight]
1141.29 |
| Chemical Properties | Back Directory | [density ]
1.50±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
Solid | [pka]
12.85±0.70(Predicted) | [color ]
White to off-white | [InChIKey]
JWINIHBXRZXFKL-SGBJXWCQSA-N |
| Hazard Information | Back Directory | [Chemical Properties]
White powder, soluble in methanol, ethanol, DMSO and other organic solvents. | [Uses]
Hosenkoside K is a baccharane glycoside isolated from the seeds of impatiens balsamina. | [in vivo]
The mean peak concentrations of hosenkoside K in rats after oral administration of total saponins of Semen Impatientis is 511.11±234.07 ng/mL, occurring at times of 0.46 h. The terminal half-lives of hosenkoside A is 4.96±1.75 h[1]. | [References]
[1] Yu X, et al. An LC-MS/MS method for simultaneous determination of hosenkoside A and hosenkoside K from Semen Impatientis in rat plasma and its application to a pharmacokinetic study. Biomed Chromatogr. 2017 Mar;31(3). DOI:10.1002/bmc.3813 |
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