ChemicalBook--->CAS DataBase List--->1660-95-3

1660-95-3

1660-95-3 Structure

1660-95-3 Structure
IdentificationMore
[Name]

Tetraisopropyl methylenediphosphonate
[CAS]

1660-95-3
[Synonyms]

METHYLENEDIPHOSPHONIC ACID TETRAISOPROPYL ESTER
TETRAISOPROPYL(METHYLENE)BISPHOSPHONATE
TETRAISOPROPYL METHYLENEDIPHOSPHONATE
Phosphonic acid, methylenebis-, tetrakis(1-methylethyl) ester
Phosphonic acid, methylenedi-, tetraisopropyl ester
phosphonicacid,methylenebis-,tetrakis(1-methylethyl)ester
tetra-i-Propylmethylenediphosphonate
Methanediphosphonic acid tetraisopropyl ester
Tetra isopropyl methylene diphospshonate
METHYLENEBIS-PHOSPHONICACID,TETRAKIS(1-METHYLETHYL)ESTER
METHYLENEPHOSPHONIC ACID TETRAISOPROPYL ESTER
Tetraisopropyl(methylene)bisphosphonate, 98 %
2-[Di(propan-2-yloxy)phosphorylmethyl-propan-2-yloxyphosphoryl]oxypropane
Bis(diisopropoxyphosphinyl)methane
Tetraisopropyl Methylenediphonate
[EINECS(EC#)]

216-765-0
[Molecular Formula]

C13H30O6P2
[MDL Number]

MFCD00015021
[Molecular Weight]

344.32
[MOL File]

1660-95-3.mol
Chemical PropertiesBack Directory
[Appearance]

Clear colorless to slightly yellow liquid
[Boiling point ]

155 °C/0.5 mmHg (lit.)
[density ]

1.08 g/mL at 25 °C(lit.)
[vapor pressure ]

0.017Pa at 20℃
[refractive index ]

n20/D 1.431(lit.)
[Fp ]

320 °F
[storage temp. ]

-20°C
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

neat
[color ]

Clear Colourless to Yellow
[Specific Gravity]

1.080
[Water Solubility ]

Insoluble in water.
[BRN ]

1080180
[InChIKey]

FKHXXJRKGVDPQP-UHFFFAOYSA-N
[LogP]

1.3 at 20℃
[CAS DataBase Reference]

1660-95-3(CAS DataBase Reference)
[NIST Chemistry Reference]

Tetraisopropyl methylenediphosphonate(1660-95-3)
[EPA Substance Registry System]

1660-95-3(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R41:Risk of serious damage to eyes.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S39:Wear eye/face protection .
[WGK Germany ]

3
[TSCA ]

Yes
[HS Code ]

29319090
Raw materials And Preparation ProductsBack Directory
[Raw materials]

1-METHYLETHYLPHOSPHONICACIDBIS(1-METHYLETHYL)ESTER-->Phosphorous acid, bis(1-methylethyl) ester-->TRIISOPROPYL PHOSPHATE
[Preparation Products]

METHYLENEDIPHOSPHONIC ACID-->METHYLENEBIS(PHOSPHONIC DICHLORIDE)-->TETRAISOPROPYL DICHLOROMETHYLENE DIPHOSPHONATE
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Tetraisopropyl methylenediphosphonate(1660-95-3).msds
Hazard InformationBack Directory
[Chemical Properties]

Clear colorless to slightly yellow liquid
[Uses]

Tetraisopropyl methylenediphosphonate [T(iPr)MDP] forms a synergistic mixture with hydrogen dicarbollylcobaltate in nitrobenzene which was used in the extraction of europium and americium.
It may be used in the synthesis of the following:
  • tetraisopropyl ethenylidenebisphosphonate.
  • tetraisopropyl 4-acetylthiobutane-1,1-diphosphonate
  • tetraisopropyl 2-(3,5-bis(bromomethyl)phenyl)ethane-1,1-diphosphonate
[Uses]

Tetraisopropyl Methylenediphosphonate is used in the preparation of E2-bisphosphonate conjugates as potential anti-osteoporosis agents. Also used in the preparation of AZT 5’-Triphosphate compounds which display inhibitory effects on HIV-1 reverse transcrpitase.
[General Description]

Tetraisopropyl methylenediphosphonate (IPCP) is a tetraisopropyl ester of methylenediphosphonic acid. It is an electroneutral ligand, reported to be synthesized from triisopropyl phosphate. Powder electron paramagnetic resonance (EPR) studies of tris complexes of Cu(II) complexes with IPCP has been analyzed.
Spectrum DetailBack Directory
[Spectrum Detail]

Tetraisopropyl methylenediphosphonate(1660-95-3)MS
Tetraisopropyl methylenediphosphonate(1660-95-3)IR1
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Tetraisopropyl methylenediphosphonate, 98%(1660-95-3)
[Alfa Aesar]

Tetraisopropyl methylenediphosphonate, 98%(1660-95-3)
[Sigma Aldrich]

1660-95-3(sigmaaldrich)
[TCI AMERICA]

Tetraisopropyl Methylenediphosphonate,>97.0%(GC)(1660-95-3)
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