ChemicalBook--->CAS DataBase List--->17092-92-1

17092-92-1

17092-92-1 Structure

17092-92-1 Structure
IdentificationBack Directory
[Name]

(2,6,6-Trimethyl-2-hydroxycyclohexylidene)acetic acid lactone
[CAS]

17092-92-1
[Synonyms]

FEMA 4020
Dihydroactinidioli
dihydroactindiolide
2(4H)-Benzofuranone
Dihydrokiwi lactone
Actinidiolide, dihydro-
(R)-Dihydroactinidiolide
(S)-dihydroactinidiolide
2(4H)-Benzofuranone,5,6,7,
4,4,7a-trimethyl-6,7-dihydro-5H-1-benzofuran-2-one
(7aR)-4,4,7a-trimethyl-6,7-dihydro-5H-benzofuran-2-one
5,6,7,7A-TETRAHYDRO-4,4,7A-TRIMETHYL-2(4H)BENZOFURANONE
2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-
(R)-5,6,7,7a-tetrahydro-4,4,7atrimethyl-2(4H)-Benzofuranone
(R)-4,4,7a-Trimethyl-5,6,7,7a-tetrahydrobenzofuran-2(4H)-one
(2,6,6-Trimethyl-2-hydroxycyclohexylidene)acetic acid lacton
(R)-5,6,7,7a-Tetrahydro-4,4,7a-trimethylbenzofuran-2(4H)-one
(2,6,6-TriMethyl-2-hydroxycyclohexylidene)acetic acid laCLone
(2,6,6-Trimethyl-2-hydroxycyclohexylidene)acetic acid lactone
(7aR)-5,6,7,7a-Tetrahydro-4,4,7aα-trimethyl-2(4H)-benzofuranone
2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-(8CI)
(R)-5,6,7,7alpha-Tetrahydro-4,4,7a-trimethyl-2(4H)-benzofuranone
2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (R)-
2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (S)-
(S)-2,6,6-Trimethyl-2-hydroxycyclohexylidene)acetic acid lactone
2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (7aR)-
(2,6,6-Trimethyl-2-hydroxycyclohexylidene)acetic acid lactone USP/EP/BP
4,4,7a-Trimethyl-5,6,7,7a-tetrahydrobenzofuran-2(4H)-one(R-Dihydroactinidiolide)
[EINECS(EC#)]

239-390-4
[Molecular Formula]

C11H16O2
[MDL Number]

MFCD06409997
[MOL File]

17092-92-1.mol
[Molecular Weight]

180.24
Chemical PropertiesBack Directory
[Melting point ]

70-71°
[alpha ]

D24 -121.0° (c = 1.05 in CHCl3)
[Boiling point ]

296.1±9.0 °C(Predicted)
[density ]

1.05±0.1 g/cm3(Predicted)
[FEMA ]

4020 | (+/-)-(2,6,6-TRIMETHYL-2-HYDROXYCYCLOHEXYLIDENE)ACETIC ACID GAMMA-LACTONE
[storage temp. ]

Sealed in dry,Room Temperature
[Odor]

musk coumarin
[JECFA Number]

1164
[LogP]

2.600
[NIST Chemistry Reference]

2(4H)-benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (r)-(17092-92-1)
Questions And AnswerBack Directory
[Biological activity]

Dihydroactinidiolide is present in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression, and is also responsible for light adaptation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotection.
[Use]

Dihydroactinidiolide is an ester organic matter, which can be used as a food flavor.
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[Safety Statements ]

24/25
[HS Code ]

29329990
Hazard InformationBack Directory
[Uses]

Dihydroactinidiolide, existing in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression and is responsible for photo acclimation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotective effect[1]. Dihydroactinidiolide is also an inhibitor of AChE (IC50=34.03 nM) and has scavenging activities for DPPH and (.NO). Dihydroactinidiolide is present in plant leaves and fruits and is a potent plant growth inhibitor, regulator of gene expression, and responsible for light adaptation in Arabidopsis.
[Definition]

ChEBI: Dihydroactinidiolide is a member of benzofurans.
[References]

[1] Das M, et al. Dihydroactinidiolide, a natural product against Aβ25-35 induced toxicity in Neuro2a cells: Synthesis, in silico and in vitro studies. Bioorg Chem. 2018 Dec;81:340-349. DOI:10.1016/j.bioorg.2018.08.037
[2] Das M, et al. Dihydroactinidiolide, a natural product against Aβ25-35 induced toxicity in Neuro2a cells: Synthesis, in silico and in vitro studies. Bioorg Chem. 2018 Dec;81:340-349. DOI:10.1016/j.bioorg.2018.08.037
Spectrum DetailBack Directory
[Spectrum Detail]

Dihydroactinidiolide(17092-92-1)1HNMR
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