| Identification | Back Directory | [Name]
(2,6,6-Trimethyl-2-hydroxycyclohexylidene)acetic acid lactone | [CAS]
17092-92-1 | [Synonyms]
FEMA 4020
Dihydroactinidioli
dihydroactindiolide
2(4H)-Benzofuranone
Dihydrokiwi lactone
Actinidiolide, dihydro-
(R)-Dihydroactinidiolide
(S)-dihydroactinidiolide
2(4H)-Benzofuranone,5,6,7,
4,4,7a-trimethyl-6,7-dihydro-5H-1-benzofuran-2-one
(7aR)-4,4,7a-trimethyl-6,7-dihydro-5H-benzofuran-2-one
5,6,7,7A-TETRAHYDRO-4,4,7A-TRIMETHYL-2(4H)BENZOFURANONE
2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-
(R)-5,6,7,7a-tetrahydro-4,4,7atrimethyl-2(4H)-Benzofuranone
(R)-4,4,7a-Trimethyl-5,6,7,7a-tetrahydrobenzofuran-2(4H)-one
(2,6,6-Trimethyl-2-hydroxycyclohexylidene)acetic acid lacton
(R)-5,6,7,7a-Tetrahydro-4,4,7a-trimethylbenzofuran-2(4H)-one
(2,6,6-TriMethyl-2-hydroxycyclohexylidene)acetic acid laCLone
(2,6,6-Trimethyl-2-hydroxycyclohexylidene)acetic acid lactone
(7aR)-5,6,7,7a-Tetrahydro-4,4,7aα-trimethyl-2(4H)-benzofuranone
2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-(8CI)
(R)-5,6,7,7alpha-Tetrahydro-4,4,7a-trimethyl-2(4H)-benzofuranone
2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (R)-
2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (S)-
(S)-2,6,6-Trimethyl-2-hydroxycyclohexylidene)acetic acid lactone
2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (7aR)-
(2,6,6-Trimethyl-2-hydroxycyclohexylidene)acetic acid lactone USP/EP/BP
4,4,7a-Trimethyl-5,6,7,7a-tetrahydrobenzofuran-2(4H)-one(R-Dihydroactinidiolide) | [EINECS(EC#)]
239-390-4 | [Molecular Formula]
C11H16O2 | [MDL Number]
MFCD06409997 | [MOL File]
17092-92-1.mol | [Molecular Weight]
180.24 |
| Chemical Properties | Back Directory | [Melting point ]
70-71° | [alpha ]
D24 -121.0° (c = 1.05 in CHCl3) | [Boiling point ]
296.1±9.0 °C(Predicted) | [density ]
1.05±0.1 g/cm3(Predicted) | [FEMA ]
4020 | (+/-)-(2,6,6-TRIMETHYL-2-HYDROXYCYCLOHEXYLIDENE)ACETIC ACID GAMMA-LACTONE | [storage temp. ]
Sealed in dry,Room Temperature | [Odor]
musk coumarin | [JECFA Number]
1164 | [LogP]
2.600 | [NIST Chemistry Reference]
2(4H)-benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (r)-(17092-92-1) |
| Questions And Answer | Back Directory | [Biological activity]
Dihydroactinidiolide is present in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression, and is also responsible for light adaptation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotection.
| [Use]
Dihydroactinidiolide is an ester organic matter, which can be used as a food flavor.
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| Hazard Information | Back Directory | [Uses]
Dihydroactinidiolide, existing in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression and is responsible for photo acclimation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotective effect[1]. Dihydroactinidiolide is also an inhibitor of AChE (IC50=34.03 nM) and has scavenging activities for DPPH and (.NO). Dihydroactinidiolide is present in plant leaves and fruits and is a potent plant growth inhibitor, regulator of gene expression, and responsible for light adaptation in Arabidopsis. | [Definition]
ChEBI: Dihydroactinidiolide is a member of benzofurans. | [References]
[1] Das M, et al. Dihydroactinidiolide, a natural product against Aβ25-35 induced toxicity in Neuro2a cells: Synthesis, in silico and in vitro studies. Bioorg Chem. 2018 Dec;81:340-349. DOI:10.1016/j.bioorg.2018.08.037
[2] Das M, et al. Dihydroactinidiolide, a natural product against Aβ25-35 induced toxicity in Neuro2a cells: Synthesis, in silico and in vitro studies. Bioorg Chem. 2018 Dec;81:340-349. DOI:10.1016/j.bioorg.2018.08.037 |
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