| Identification | Back Directory | [Name]
euscaphic acid | [CAS]
53155-25-2 | [Synonyms]
euscaphicaci
Euscapic acid
Euscophic acid
euscaphic acid
Acuminatic acid
Jacarandic acid
Urs-12-en-28-oic acid,2,3,19-trihydroxy-, (2a,3a)- | [EINECS(EC#)]
200-258-5 | [Molecular Formula]
C30H48O5 | [MDL Number]
MFCD09970922 | [MOL File]
53155-25-2.mol | [Molecular Weight]
488.704 |
| Chemical Properties | Back Directory | [Melting point ]
262-264 °C(Solv: chloroform (67-66-3); methanol (67-56-1)) | [Boiling point ]
602.7±55.0 °C(Predicted) | [density ]
1.19±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Methanol (Slightly), Pyridine (Slightly) | [form ]
Solid | [pka]
4.47±0.70(Predicted) | [color ]
White to Off-White | [InChIKey]
OXVUXGFZHDKYLS-SPQMEPECSA-N | [SMILES]
C[C@H]1[C@](O)(C)[C@H]2[C@@](C(=O)O)(CC[C@]3([C@@]4(C)[C@@H]([C@@]5(C(CC4)C(C)(C)[C@H](O)[C@H](O)C5)C)CC=C32)C)CC1 |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from the roots of golden cherry and the seeds of Fujian wild jasmine. | [Uses]
Euscaphic Acid is a hypoglycemic natural product from Folium Eriobotryae with anti-inflammatory properties. Euscaphic Acid also downregulates NF-κB activations and inhibits LPS-induced inflammatory responses. | [Definition]
ChEBI: Euscaphic acid is a pentacyclic triterpenoid that is urs-12-en-28-oic acid substituted by hydroxy groups at positions 2, 3 and 19 respectively (the 2alpha,3alpha-stereoisomer). It has been isolated from the leaves of Rosa laevigata. It has a role as a plant metabolite. It is a pentacyclic triterpenoid, a hydroxy monocarboxylic acid and a triol. It derives from a hydride of an ursane. | [target]
LDL | NO | PGE | TNF-α | NOS | COX | NF-kB | JNK | ERK | p38MAPK | Calcium Channel | Sodium Channel | ATPase | Potassium Channel | IkB | IKK |
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