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173901-95-6

173901-95-6 Structure

173901-95-6 Structure
IdentificationBack Directory
[Name]

Benzenesulfonamide, 4-[4-(3-cyclopentylpropyl)-4,5-dihydro-5-oxo-1H-tetrazol-1-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]-
[CAS]

173901-95-6
[Synonyms]

L770644
L-770644
L 770644
L 770644,L770644
Benzenesulfonamide, 4-[4-(3-cyclopentylpropyl)-4,5-dihydro-5-oxo-1H-tetrazol-1-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]-
[Molecular Formula]

C30H37N7O4S
[MDL Number]

MFCD04112995
[MOL File]

173901-95-6.mol
[Molecular Weight]

591.72
Chemical PropertiesBack Directory
[Boiling point ]

755.0±70.0 °C(Predicted)
[density ]

1.36±0.1 g/cm3(Predicted)
[pka]

8.69±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

L-770644 is an orally active, potent and selective agonist of the human β3 adrenergic receptor (EC50 = 13 nM)[1].
[IC 50]

Beta-3 adrenergic receptor: 13 nM (EC50)
[References]

[1] Shih TL, et al. L-770,644: a potent and selective human beta3 adrenergic receptor agonist with improved oral bioavailability. Bioorg Med Chem Lett. 1999 May 3;9(9):1251-4. DOI:10.1016/s0960-894x(99)00182-1
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