| Identification | Back Directory | [Name]
SPINETORAM | [CAS]
187166-40-1 | [Synonyms]
SPINETORAM
Spinetoram J
Spinetoram certified
Spinetoram (major component)
3'-Ethoxy-5,6-dihydrospinosyn J
Spinetoram (major component) [iso]
spinosyn J, 3'-Ethoxy-5,6-dihydro-
Spinetoram, 10 μg /μL in acetonitrile
Spinetoram@1000 μg/mL in Acetonitrile
Spinetoram @100 μg/mL in Acetonitrile
1H-as-Indaceno[3,2-d]oxacyclododecin-7,15-dione, 2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-α-L-mannopyranosyl)oxy]-13-[[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-9-ethyl-2,3,3a,4,5,5a,5b,6,9,10,11,12,13,14,16a,16b-hexadecahydro-14-methyl-, (2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)- | [Molecular Formula]
C42H69NO10 | [MDL Number]
MFCD11616778 | [MOL File]
187166-40-1.mol | [Molecular Weight]
748.004 |
| Chemical Properties | Back Directory | [Boiling point ]
803.5±65.0 °C(Predicted) | [density ]
1.15±0.1 g/cm3(Predicted) | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
8.62±0.60(Predicted) | [color ]
White to Pale Yellow | [InChIKey]
GOENIMGKWNZVDA-PAHYXNTPNA-N | [EPA Substance Registry System]
1H-as-Indaceno[3,2-d]oxacyclododecin-7,15-dione, 2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-.alpha.-L-mannopyranosyl)oxy]-13-[[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-9-ethyl-2,3,3a,4,5,5a,5b,6,9,10,11,12,13,14,16a,16b-hexadecahydro-14-methyl-, (2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)- (187166-40-1) |
| Hazard Information | Back Directory | [Uses]
3'-Ethoxy-5,6-dihydrospinosyn J is the major component in the second generation spinosyn family of bio-insecticides marketed as Spinetoram. 3'-Ethoxy-5,6-dihydrospinosyn J is a semi-synthetic compound prepared by selective ethylation and hydrogenation of Spinosyn J, itself a fermentation product from a biosynthetically blocked mutant of Saccharopolyspora spinosa. As an insecticide, 3'-ethoxy-5,6-dihydrospinosyn J is considered more potent, and to have earlier onset and longer duration of action than combinations of spinosyn A and D. | [Production Methods]
Spinetoram J is not manufactured through a single chemical synthesis but through a semi synthetic upgrade of natural spinosyns produced by Saccharopolyspora spinosa. The process begins with microbial fermentation, where a genetically modified strain is engineered to block a specific O methylation step, causing the organism to accumulate the precursor 5,6 dihydrospinosyn J. This fermentation product is then subjected to selective chemical modification, most notably 3′ O ethylation, to yield spinetoram J as one of the two active components of commercial spinetoram. The resulting semi synthetic molecule is purified to agrochemical grade and blended with spinetoram L to form the final insecticidal active ingredient. | [Mechanism of action]
Shows high residual, contact and ingestion activity. Nicotinic acetylcholine receptor (nAChR) channel blocker - site I | [Pesticide Type]
Insecticide |
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