19056-75-8

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19056-75-8 Structure

Identification	Back Directory
[Name] 5-Hydroxy-2′,3,4′,7-tetramethoxyflavone
[CAS] 19056-75-8
[Synonyms] 5-Hydroxy-2′,3,4′,7-tetramethoxyflavone 2-(2,4-dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one
[Molecular Formula] C19H18O7
[MOL File] 19056-75-8.mol
[Molecular Weight] 358.34

Hazard Information	Back Directory
[Uses] BCRP/ABCG2-IN-1 is the inhibitor of breast cancer resistance protein (BCRP/ABCG2), with IC50 of 5.98 μM, that can be used in multidrug resistance of breast cancer[1].
[References] [1] Kapil Juvale, et al. Synthesis and biological evaluation of flavones and benzoflavones as inhibitors of BCRP/ABCG2. Eur J Med Chem. 2013 Sep:67:115-26. DOI:10.1016/j.ejmech.2013.06.035

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