| Identification | More | [Name]
2-PYRAZINECARBONYL CHLORIDE | [CAS]
19847-10-0 | [Synonyms]
2-PYRAZINECARBONYL CHLORIDE
ASINEX-REAG BAS 07703829
PYRAZINE-2-CARBONYL CHLORIDE
PYRAZINE-2-CARBOXYLIC ACID CHLORIDE
TIMTEC-BB SBB010290
pyrazinecarbonyl chloride
2-PYRAZINECARBONYL CHLORIDE: TECH. | [EINECS(EC#)]
243-367-4 | [Molecular Formula]
C5H3ClN2O | [MDL Number]
MFCD00792886 | [Molecular Weight]
142.54 | [MOL File]
19847-10-0.mol |
| Safety Data | Back Directory | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
3265 | [HazardClass ]
8 | [PackingGroup ]
II |
| Hazard Information | Back Directory | [Uses]
2-Pyrazinecarbonyl Chloride is an intermediate used in the synthesis of (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2yl]pyrazine-2-carboxamide (H805105), which is an impurity of bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway. |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
NovoChemy Ltd.
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| Telephone: |
86-(0)21-31261262 373522135 |
| Website: |
www.novochemy.com |
| Company Name: |
SPIRO PHARMA
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| Telephone: |
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| Website: |
www.spiropharma.com.cn |
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