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20071-00-5

20071-00-5 Structure

20071-00-5 Structure
IdentificationBack Directory
[Name]

Angiotensin acetate
[CAS]

20071-00-5
[Synonyms]

Angiotensin Acetat
(asn1,val5)-angiotensin ii acetate
[ASN1, VAL5]-ANGIOTENSIN II ACETATE SALT
ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE ACETATE SALT
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,4-diamino-4-oxobutanoyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
[EINECS(EC#)]

215-804-9
[Molecular Formula]

C51H74N14O13
[MDL Number]

MFCD00133941
[MOL File]

20071-00-5.mol
[Molecular Weight]

1091.22
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[form ]

powder
[InChIKey]

JYPVVOOBQVVUQV-CGHBYZBKSA-N
Safety DataBack Directory
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

[Asn1, Val5]-Angiotensin II has been used:
  • to study the effects of ACTH, serotonin, Ang II, carbachol and elevated [K+] on catecholamine and serotonin release
  • to induce cyclophilin D (CypD)–dependent mitochondrial vascular superoxide (O2. - ) production in hypertension
  • to increase the homocysteine-induced ER stress-inducible, ubiquitin-like domain member 1 (HERPUD1) protein level in HeLa cells

[General Description]

Angiotensin II is a renin-angiotensin system (RAS) effector molecule, which binds to angiotensin II type-1 (AT1R) and angiotensin II type-2 (AT2R) receptors. The gene is located on human chromosome 3q24. Angiotensin II is mainly expressed in vessel walls, lung and kidney.
[Biochem/physiol Actions]

Synthetic angiotensin agonist that is involved in the regulation of blood pressure, water consumption, and hydromineral balance in fish.
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