| Identification | More | [Name]
Tocopheryl acetate | [CAS]
7695-91-2 | [Synonyms]
[2r-[2r*(4r*,8r*)]]-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2h-1-benzopyran-6-ol acetate
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
ALL-RAC-ALPHA-TOCOPHERYL ACETATE
(+/-)-ALPHA-TOCOPHEROL ACETATE
ALPHA-TOCOPHERYL ACETATE
ALPHA-TOCOPHERYLIS ACETAS
(+)-A-TOCOPHEROL
DL-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)-6-CHROMANOL ACETATE
DL-ALFACOL
DL-ALPHA-TOCOPHEROL ACETATE
DL-ALPHA-TOCOPHERYL ACETATE
DL-A-TOCOPHEROL ACETATE
DL-A-TOCOPHERYL ACETATE
DL-CONTOPHERON
DL-ECON
DL-FERTILVIT
DL-TOCOPHRIN
DL-VITAMIN E ACETATE
EPSILAN-M
O-ACETYL-ALPHA-TOCOPHEROL | [EINECS(EC#)]
231-710-0 | [Molecular Formula]
C31H52O3 | [MDL Number]
MFCD00072042 | [Molecular Weight]
472.74 | [MOL File]
7695-91-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
-28°C | [Boiling point ]
224 °C0.3 mm Hg(lit.)
| [density ]
0.96 g/mL at 20 °C(lit.)
| [vapor density ]
16.3 (vs air)
| [refractive index ]
n20/D 1.497
| [Fp ]
>230 °F
| [storage temp. ]
2-8°C
| [solubility ]
Practically insoluble in water, freely soluble in acetone, in anhydrous ethanol and in fatty oils. | [form ]
neat | [color ]
Clear yellow viscous liquid | [Specific Gravity]
0.962 (20/4℃) | [Odor]
Odorless | [Water Solubility ]
Immiscible with water. | [Sensitive ]
Air & Light Sensitive | [Merck ]
14,9495 | [BRN ]
97512 | [Contact allergens]
Tocopherol and tocopheryl acetate are used mainly as
antioxidants. Tocopheryl acetate, an ester of tocopherol
(vitamin E), can induce allergic contact dermatitis. | [InChIKey]
ZAKOWWREFLAJOT-CEFNRUSXSA-N | [LogP]
12.260 (est) | [Uses]
vitamin E acetate (tocopherol acetate,7695-91-2) is an anti-oxidant with skinmoisturizing activity. given its free-radical scavenging properties, it is useful in uV protective products. Vitamin e acetate is commonly used to replace vitamin e because it is more stable and is converted to vitamin e by the body.
| [CAS DataBase Reference]
7695-91-2(CAS DataBase Reference) | [NIST Chemistry Reference]
(+)-«ALPHA»-tocopherol acetate(7695-91-2) | [EPA Substance Registry System]
7695-91-2(EPA Substance) |
| Hazard Information | Back Directory | [Chemical Properties]
Light yellow to yellow clear liquid | [Uses]
anti-Altzheimer therapeutic | [Definition]
ChEBI:DL-alpha-Tocopherol acetate is a tocol. | [General Description]
DL-α-Tocopherol acetate is a stable ester form of vitamin E, widely used in the formulation of cosmetics for the prevention or correction of skin damage. | [Hazard]
A reproductive hazard. | [Flammability and Explosibility]
Nonflammable | [Biochem/physiol Actions]
Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by Homosapiens. DL-α-Tocopherol acetate can inhibit oxidation of linoleate. | [storage]
Store at -20°C | [Purification Methods]
It is a viscous liquid which is purified by distillation under high vacuum under N2 or Ar and stored in sealed ampoules in the dark. It is considerably more stable to light and air than the parent unacetylated vitamin. It is insoluble in H2O but freely soluble in organic solvents. All eight stereoisomers have been synthesised. The commercially pure d-tocopheryl acetate (2R,4'R,8'R) has b 180-200o/0.7mm and [] D 20 +3.9o (c 5, EtOH); see above. [Cohen et al. Helv Chim Acta 64 1158 1981, Beilstein 17/4 V 169.] |
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