ChemicalBook--->CAS DataBase List--->20280-81-3

20280-81-3

20280-81-3 Structure

20280-81-3 Structure
IdentificationMore
[Name]

4-METHOXYCOUMARIN
[CAS]

20280-81-3
[Synonyms]

4-METHOXY-2H-CHROMEN-2-ONE
4-METHOXYCOUMARIN
4-METHOXYCOUMARINE
METHOXYCOUMARIN,4
[Molecular Formula]

C10H8O3
[MDL Number]

MFCD00017349
[Molecular Weight]

176.17
[MOL File]

20280-81-3.mol
Chemical PropertiesBack Directory
[Melting point ]

123-125°C
[Boiling point ]

347.8±37.0 °C(Predicted)
[density ]

1.26±0.1 g/cm3(Predicted)
[storage temp. ]

Refrigerator
[solubility ]

Acetonitrile (Slightly), Chloroform (Slightly), Dichloromethane (Slightly), DMSO
[form ]

Solid
[color ]

White to Off-White
[Odor]

Faintly herbaceous, sweet and very tenacious odor.
[BRN ]

145960
[LogP]

1.840 (est)
[CAS DataBase Reference]

20280-81-3(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
Hazard InformationBack Directory
[Uses]

4-Methoxycoumarin (Compound 6) shows antibacterial activity of against R. solanacearum[1].
[Production Methods]

4-Methoxycoumarin is produced from 4-Hydroxycoumarinwith Diazomethane. 4-Hydroxycoumarin may be obtained from Diphenylmalonate by cyclization with Aluminum chloride. It has also been prepared from Methyl acetylsalicylate by treatment with Sodium in liquid paraffin at 240 ℃.
[References]

[1] Yang L, et al. New Insights into the Antibacterial Activity of Hydroxycoumarins against Ralstonia solanacearum. Molecules. 2016 Apr 8;21(4):468. DOI:10.3390/molecules21040468
Spectrum DetailBack Directory
[Spectrum Detail]

4-METHOXYCOUMARIN(20280-81-3)MS
4-METHOXYCOUMARIN(20280-81-3)1HNMR
4-METHOXYCOUMARIN(20280-81-3)IR1
4-METHOXYCOUMARIN(20280-81-3)IR2
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

4-Methoxycoumarin, 98%(20280-81-3)
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