| Identification | More | [Name]
4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN | [CAS]
88404-25-5 | [Synonyms]
4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN
4-(BROMOMETHYL)-6,7-DIMETHOXYCOUMARIN, 9 7%
4-(Bromomethyl)-6,7-dimethoxycoumarine
4-Bromomethyl-6,7-dimethoxycoumarin [for HPLC Labeling]
4-(Bromomethyl)-6,7-dimethoxy-2H-1-benzopyran-2-one | [Molecular Formula]
C12H11BrO4 | [MDL Number]
MFCD00011570 | [Molecular Weight]
299.12 | [MOL File]
88404-25-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Light Greenish-Yellow Powder | [Melting point ]
212-216 °C(lit.) | [density ]
1.6176 (rough estimate) | [refractive index ]
1.4490 (estimate) | [storage temp. ]
Refrigerator | [solubility ]
Soluble in acetonitrile, dichloromethane,
N,N-dimethylformamide, methanol | [color ]
Yellow crystals or powder | [Water Solubility ]
Insoluble in water. | [Usage]
A fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids | [λmax]
348 nm (MeOH) | [BRN ]
4750487 | [Biological Applications]
Analyzing bile
acid; anticancer agents; identifying bacteria;
identifying/measuring lauric acid metabolites;
measuring cyclosporine; studying/monitoring early
stages of protein folding;treating gastrointestinal
diseases; derivatization reagent for carboxylic
acids; as a substrate for measuring lauric acid
hydroxylase activity | [Major Application]
Electrostatic imaging
process; resists; printed circuit boards;
semiconductor devices | [CAS DataBase Reference]
88404-25-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,C | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
1759 | [WGK Germany ]
3
| [F ]
21 | [Hazard Note ]
Corrosive | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29322090 |
| Hazard Information | Back Directory | [Chemical Properties]
Light Greenish-Yellow Powder | [Uses]
4-Bromomethyl-6,7-dimethoxycoumarin was used as fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids. It was also used as derivatization reagent:
- for quantitation of clofibric, bezafibric and fenofibric acids in liver by liquid chromatography
- in determination of the concentration of tripeptide glutathione by matrix-assisted laser desorption ionization time-of-flight mass spectrometry
- for determination of carboxylic acids in chromatographic detection
| [Uses]
4-Bromomethyl-6,7-dimethoxycoumarin is used as fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids. It is also used as derivatization reagent: for quantitation of clofibric, bezafibric and fenofibric acids in liver by liquid chromatography, in determination of the concentration of tripeptide glutathione by matrix-assisted laser desorption ionization time-of-flight mass spectrometry and for determination of carboxylic acids in chromatographic detection. | [Uses]
A fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids |
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