| Identification | More | [Name]
Benperidol | [CAS]
2062-84-2 | [Synonyms]
1-[1-[4-(4-FLUOROPHENYL)-4-OXOBUTYL]PIPERIDIN-4-YL]-1H-BENZO[D]IMIDAZOL-2(3H)-ONE
1-(1-(3-(p-fluorobenzoyl)propyl)-4-piperidyl)-2-benzimidazolinon
1-(1-(3-(p-fluorobenzoyl)propyl)-4-piperidyl)-2-benzimidazolinone
1-(4-Fluorophenyl)-4-[4-(2-hydroxy-1H-benzimidazol-1-yl)-1-piperidinyl]-1-butanone
1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
1-1-(3-(p-Fluorobenzoyl)propyl)-4-piperidyl-2-benzimidazolinone
2-Benzimidazolinone, 1-[1-[3-(p-fluorobenzoyl)propyl]-4-piperidyl]-
2H-Benzimidazol-2-one, 1-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1,3-dihydro-
2h-benzimidazol-2-one,1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidinyl)-1,
8089 C. B.
8089c.b.
Anquil
Benzeridol
Benzoperidol
Benzperidol
Concilium
Frenactil
Frenactyl
Glianimon
Glianimon mite | [EINECS(EC#)]
218-172-2 | [Molecular Formula]
C22H24FN3O2 | [MDL Number]
MFCD00866672 | [Molecular Weight]
381.44 | [MOL File]
2062-84-2.mol |
| Chemical Properties | Back Directory | [Appearance]
White or almost white powder. | [Melting point ]
170-171.8° | [Boiling point ]
230.3°C (rough estimate) | [density ]
1.1876 (estimate) | [storage temp. ]
Store at -20°C | [solubility ]
Practically insoluble in water, freely soluble in dimethylformamide, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). | [form ]
neat | [pka]
12.04±0.30(Predicted) | [color ]
White to off-white | [Major Application]
pharmaceutical (small molecule) | [InChI]
1S/C22H24FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28) | [InChIKey]
FEBOTPHFXYHVPL-UHFFFAOYSA-N | [SMILES]
Fc1ccc(cc1)C(=O)CCCN2CCC(CC2)[n]3c4c([nH][c]3=O)cccc4 | [CAS DataBase Reference]
2062-84-2(CAS DataBase Reference) | [NIST Chemistry Reference]
Benperidol(2062-84-2) |
| Hazard Information | Back Directory | [Chemical Properties]
White or almost white powder. | [Originator]
Frenactil,Clin-Comar-Byla,France,1965 | [Uses]
Antipsychotic. | [Definition]
ChEBI: 3-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1H-benzimidazol-2-one is an aromatic ketone. | [Manufacturing Process]
A mixture of 3.4 parts of γ-chloro-4-fluorobutyrophenone, 4 parts of 1-(4-
piperidyl)-2-benzimidazolinone hydrochloride, 6 parts of sodium carbonate and
0.1 part of potassium iodide in 176 parts of 4-methyl-2-pentanone is stirred
and refluxed for 48 hours. The reaction mixture is cooled and 120 parts of
water is added. The separated organic layer is dried over magnesium sulfate
and the solvent is evaporated to leave an oily residue which is dissolved in
dilute hydrochloric acid and boiled. The acidic solution is filtered and cooled at
room temperature whereupon there crystallizes from solution 1-(1-[γ-(4-
fluorobenzoyl)propyl] -4-piperidyl)-2-benzimidazolinone hydrochloride hydrate
melting at about 134°-142°C. | [Therapeutic Function]
Tranquilizer |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Shaanxi Dideu Medichem Co. Ltd
|
| Telephone: |
+86-29-81139210 17389186172 |
| Website: |
https://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-219/ |
|