| Identification | More | [Name]
Gestonorone | [CAS]
2137-18-0 | [Synonyms]
17a-hydroxy-19-norpregn-4-ene-3,20-dione
17a-hydroxy-19-norprogesterone
17ALPHA-HYDROXY-19-NORPREGN-4-EN-3,20-DIONE
17-hydroxy-19-norpregn-4-ene-3,20-dione
19-NOR-4-PREGNEN-17-OL-3,20-DIONE
GESTONORONE
17-alpha-hydroxy-19-norpregn-4-ene-3,20-dione
GESTONORONE BASE:17ALPHA-HYDROXY-19-NORPREGN-4-EN-3,20-DIONE
19-Nor-4-pregene-17-ol-3,20-dione
Gestronol
19-nor-17-α-hydroxyprogesterone
17a-Hydroxy-19-norpregn-4-ene-3,20-dione | [EINECS(EC#)]
218-378-2 | [Molecular Formula]
C20H28O3 | [MDL Number]
MFCD03695613 | [Molecular Weight]
316.43 | [MOL File]
2137-18-0.mol |
| Hazard Information | Back Directory | [Uses]
Gestonorone is a steroidal progestin. It has been shown to have accelerated body weight gain and caused the atrophy of the prostate, uterus, and seminal vesicles in rats. It is also an inhibitor of the reductive pathway of Testosterone (T155000) metabolism. | [Definition]
ChEBI: Gestonorone is a corticosteroid hormone. | [Synthesis]
A solution of (17α)-3-methoxy-17-[(trimethylsilyl)-oxy]-estra-2,5(10)-dien-17-ylmethylnitril in 600 ml of methyl tert-butyl ether was cooled with stirring to -40 °C, and then 80 ml of N,N,N′,N′-tetramethylethylenediamine and 180 ml of lithium methoxide (3 |
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