| Identification | Back Directory | [Name]
4-Cyano-2-fluorobenzyl alcohol | [CAS]
219873-06-0 | [Synonyms]
4-Cyano-2-fluorobenzyl alcohol
3-Fluoro-4-(hydroxymethyl)benzonitrile
Benzonitrile, 3-fluoro-4-(hydroxymethyl)-
3-Fluoro-4-(hydroxymethyl)benzonitrile 97%
3-Fluoro-4-(hydroxymethyl)benzonitrile99+%
Benzonitrile, 3-fluoro-4-(hydroxymethyl)- (9CI)
4-Cyano-2-fluorobenzyl alcohol ISO 9001：2015 REACH
3-Fluoro-4-(hydroxyMethyl)-benzonitrile[4-cyano--2-fluorobenzyl alcohol | [Molecular Formula]
C8H6FNO | [MDL Number]
MFCD09037779 | [MOL File]
219873-06-0.mol | [Molecular Weight]
151.14 |
| Chemical Properties | Back Directory | [Melting point ]
63-68°C | [Boiling point ]
288.8±30.0 °C(Predicted) | [density ]
1.27 g/mL at 25 °C | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
crystalline powder | [pka]
13.51±0.10(Predicted) | [color ]
Faint/pale lemon/gold | [InChI]
InChI=1S/C8H6FNO/c9-8-3-6(4-10)1-2-7(8)5-11/h1-3,11H,5H2 | [InChIKey]
YGAURRAHPYQHDC-UHFFFAOYSA-N | [SMILES]
C(#N)C1=CC=C(CO)C(F)=C1 |
| Hazard Information | Back Directory | [Uses]
4-Cyano-2-fluorobenzyl alcohol is an essential drug intermediate and is widely applied to the synthesis of various drugs. For example: S1P1 Receptor agonists, drugs for treating Alzheimer's disease BMS708163, amides for treating arrhythmia, etc.
| [Synthesis]
4-Cyano-2-fluorobenzyl alcohol, also known as 3-fluoro-4-hydroxymethylbenzonitrile, can be obtained by the reaction of 2-fluoro-4-bromobenzyl alcohol with zinc cyanide or by reduction of 4-cyano-2-fluorobenzoic acid methyl ester. To a solution o |
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