ChemicalBook--->CAS DataBase List--->2203-97-6

2203-97-6

2203-97-6 Structure

2203-97-6 Structure
IdentificationBack Directory
[Name]

Hydrocortisone 21-hemisuccinate
[CAS]

2203-97-6
[Synonyms]

C12888
saxizon
NSC 7576
-2-oxoethoxy)
cortisolsuccinate
Hydrocortisone 21-he
CORTISOL HEMISUCCINATE
Hydrocortizone Succinate
HYDROCORTISONE SUCCINATE
CORTISOL 21-HEMISUCCINATE
20-dione 21-hemisuccinate
21-Trihydroxy-4-pregnene-3
cortisol,hydrogensuccinate
HYDROXYCORTISONE SUCCINATE
hydrocortisone21-succinate
Hydrocortisone Succinate RS
HYDROCORTISONE HEMISUCCINATE
HYDROCORTISONE 21-HEMISUCCINATE
cortisol,21-(hydrogensuccinate)
HYDROCORTISONE HYDROGEN SUCCINATE
4-(2-((8S,9S,10R,11S,13S,14S,17R)
Hydrocortisone acetate half Kohaku
Cortisol, hydrogen succinate (7CI)
Hydrocortisone hydrogen succinate CRS
hydrocortisone 21-(hydrogen succinate)
HYDROCORTISONEHEMISUCCINATE(ANHYDROUS)
Cortisol 21-(4-oxo-4-hydroxybutanoate)
Cortisol, 21-(hydrogen succinate) (8CI)
hydrocortisone 21-hemisuccinate*free acid
Hydrocortisone 21-hemisuccinate USP/EP/BP
4-PREGNEN-11-BETA, 17,21-TRIOL-3,20-DIONE 21-HEMISUCCINATE
11β,17α,21-trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate
11b,17a,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate
4-PREGNEN-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 21-HEMISUCCINATE
21-(3-Carboxy-1-oxopropoxy)-11β,17-dihydroxypregn-4-ene-3,20-dione
21-(3-Carboxy-1-oxopropoxy)-11β,17α-dihydroxypregn-4-ene-3,20-dione
11BETA,17ALPHA,21-TRIHYDROXY-4-PREGNENE-3,20-DIONE 21-HEMISUCCINATE
11beta,17,21-Trihydroxypregn-4-ene-3,20-dione21-(hydrogensuccinate)
17-dihydroxy-20-dion(11-beta)-preg-4-ene-21-(3-carboxy-1-oxopropoxy)-11
(11-beta)-21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxypreg-4-ene-3,20-dione
Pregn-4-ene-3,20-dione,21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, (11b)-
Pregn-4-ene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, (11β)-
-11,17-Dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)
4-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid
4-(2-((8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethoxy)-4-oxobutanoic acid
[EINECS(EC#)]

218-612-3
[Molecular Formula]

C25H34O8
[MDL Number]

MFCD00046256
[MOL File]

2203-97-6.mol
[Molecular Weight]

462.53
Chemical PropertiesBack Directory
[Appearance]

White or almost white, hygroscopic powder
[Melting point ]

170~172℃
[alpha ]

[α]D20 +147~+153° (c=1, C2H5OH) (After Drying)
[Boiling point ]

685.5±55.0 °C(Predicted)
[density ]

1.33±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
[solubility ]

Practically insoluble in water, freely soluble in acetone and in anhydrous ethanol. It dissolves in dilute solutions of alkali carbonates and alkali hydroxides.
[form ]

neat
[pka]

pKa 5.10/5.64(20% aq EtOH/50% aq EtOH) (Uncertain)
[color ]

White to Off-White
Hazard InformationBack Directory
[Chemical Properties]

White or almost white, hygroscopic powder
[Uses]

glucocorticoid
[Definition]

ChEBI: A derivative of succinic acid in which one of the carboxy groups is esterified by the C-21 hydroxy group of cortisol (hydrocortisone).
[Brand name]

A-Hydrocort (Abbott); A-Hydrocort (Hospira); Solu-Cortef (Pharmacia & Upjohn).
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
[RTECS ]

TU5010147
Spectrum DetailBack Directory
[Spectrum Detail]

Hydrocortisone 21-hemisuccinate(2203-97-6)1HNMR
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