| Identification | More | [Name]
4-(Difluoromethoxy)aniline | [CAS]
22236-10-8 | [Synonyms]
4-AMINO-ALPHA,ALPHA-DIFLUOROANISOLE
4-(DIFLUOROMETHOXY)ANILINE
AKOS B014415
AKOS BBS-00000568
ALPHA,ALPHA-DIFLUORO-P-ANISIDINE
ART-CHEM-BB B014415
BUTTPARK 45\03-44
P-DIFLUOROMETHOXYANILINE
TIMTEC-BB SBB003981
4-(Difluoromethoxy)aniline 98%
4-(Difluoromethoxy)aniline98%
4-(Difluoromethoxy)aniine
4-Difluoromethoxy-phenylamine | [EINECS(EC#)]
625-478-3 | [Molecular Formula]
C7H7F2NO | [MDL Number]
MFCD00085005 | [Molecular Weight]
159.13 | [MOL File]
22236-10-8.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear colorless to orange-brown liquid | [Boiling point ]
231 °C (lit.) | [density ]
1.283 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.505(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [form ]
clear liquid | [pka]
4.15±0.10(Predicted) | [color ]
Light yellow to Amber to Dark green | [Specific Gravity]
1.283 | [BRN ]
2804462 | [InChI]
1S/C7H7F2NO/c8-7(9)11-6-3-1-5(10)2-4-6/h1-4,7H,10H2 | [InChIKey]
NDEZTSHWEPQVBX-UHFFFAOYSA-N | [SMILES]
Nc1ccc(OC(F)F)cc1 | [CAS DataBase Reference]
22236-10-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,T,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R43:May cause sensitization by skin contact. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves . | [RIDADR ]
UN 2811 6.1/PG 3
| [WGK Germany ]
2
| [Hazard Note ]
Toxic | [HazardClass ]
6.1 | [HazardClass ]
IRRITANT | [PackingGroup ]
Ⅲ | [HS Code ]
29222990 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colorless to orange-brown liquid | [Uses]
4-(Difluoromethoxy)aniline serves as a starting material for the synthesis of BMS-665053, where it undergoes one-step oxidative bis-ortho-chlorination to construct aniline D[1]. | [References]
[1] Kocieňski, P. (2012). Synthesis of BMS-665053. Synfacts, 8 1, 0354–0354. https://doi.org/10.1055/s-0031-1290483
|
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
China Langchem Inc.
|
| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
|