| Identification | More | [Name]
3,3,3-TRIFLUORO-1-PROPANOL | [CAS]
2240-88-2 | [Synonyms]
3,3,3-TRIFLUORO-1-PROPANOL
3,3,3-TRIFLUOROPROPAN-1-OL
3,3,3-TRIFLUOROPROPANOL
3,3,3-TRIFLUOROPROPANOL-1
3,3,3-Trifluoropropan-1-ol 97%
3,3,3-Trifluoropropan-1-ol97% | [EINECS(EC#)]
670-540-5 | [Molecular Formula]
C3H5F3O | [MDL Number]
MFCD00190649 | [Molecular Weight]
114.07 | [MOL File]
2240-88-2.mol |
| Chemical Properties | Back Directory | [Boiling point ]
100 °C | [density ]
1,294 g/cm3 | [refractive index ]
1.32 | [Fp ]
37°C | [storage temp. ]
Sealed in dry,2-8°C | [form ]
clear liquid | [pka]
14.09±0.10(Predicted) | [color ]
Colorless to Almost colorless | [Specific Gravity]
1.294 | [Water Solubility ]
Fully miscible in water. | [BRN ]
1734777 | [InChI]
InChI=1S/C3H5F3O/c4-3(5,6)1-2-7/h7H,1-2H2 | [InChIKey]
HDBGBTNNPRCVND-UHFFFAOYSA-N | [SMILES]
C(O)CC(F)(F)F | [CAS DataBase Reference]
2240-88-2(CAS DataBase Reference) | [EPA Substance Registry System]
3,3,3-Trifluoropropan-1-ol (2240-88-2) |
| Safety Data | Back Directory | [Hazard Codes ]
F | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
1987 | [WGK Germany ]
WGK 3 | [Hazard Note ]
Flammable | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29055900 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colorless liquid | [Uses]
3,3,3-Trifluoro-1-propanol is a important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field. | [Synthesis]
General procedure for the synthesis of 3,3,3-trifluoro-1-propanol from 2-bromo-3,3,3-trifluoropropan-1-ol: 54 g of 2-bromo-3,3,3-trifluoropropan-1-ol, 79 g of methanol, 9.7 g of activated Raney Ni catalyst and 19.3 g of potassium carbonate were added to a 300 mL autoclave. The reaction system was evacuated and displaced three times with hydrogen under stirring conditions. Subsequently, the hydrogen pressure was adjusted to 5 MPa and heated to 80°C. The reaction lasted for 3.0 hours. Upon completion of the reaction, the heating was stopped, the reaction mixture was cooled and the pressure was released. Finally, the target product 3,3,3-trifluoro-1-propanol was obtained by distillation purification in 95.0% yield. | [References]
[1] Patent: CN105399607, 2016, A. Location in patent: Paragraph 0022; 0023 |
|
|