| Identification | More | [Name]
1,3-Dichloro-2-fluorobenzene | [CAS]
2268-05-5 | [Synonyms]
1,3-DICHLORO-2-FLUOROBENZENE
2,6-DICHLOROFLUOROBENZENE
Benzene,1,3-dichloro-2-fluoro-
2,6-DichloroFluorobenzene99%
2,6-Dichloro Fluorobenzene 99%
1,3-Dichloro-2-fluorobenzene, 98+%
2,6-dichloro-1-fluorobenzene
2,6-Dichlorfluorbenzol
2,6-dichloro-benzenamin | [EINECS(EC#)]
607-128-1 | [Molecular Formula]
C6H3Cl2F | [MDL Number]
MFCD00010307 | [Molecular Weight]
164.99 | [MOL File]
2268-05-5.mol |
| Chemical Properties | Back Directory | [Appearance]
slightly beige transparent crystals | [Melting point ]
37-40 °C(lit.)
| [Boiling point ]
168-169 °C(lit.)
| [density ]
1.3967 (estimate) | [Fp ]
140 °F
| [storage temp. ]
Sealed in dry,Room Temperature | [form ]
powder to crystal | [color ]
White to Light yellow to Light orange | [BRN ]
1862513 | [InChI]
InChI=1S/C6H3Cl2F/c7-4-2-1-3-5(8)6(4)9/h1-3H | [InChIKey]
JORVCRLRRRRLFI-UHFFFAOYSA-N | [SMILES]
C1(Cl)=CC=CC(Cl)=C1F | [CAS DataBase Reference]
2268-05-5(CAS DataBase Reference) | [NIST Chemistry Reference]
1,3-Dichloro-2-fluorobenzene(2268-05-5) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [RIDADR ]
UN 1325 4.1/PG 2
| [WGK Germany ]
2
| [Hazard Note ]
Irritant | [HazardClass ]
4.1 | [PackingGroup ]
III | [HS Code ]
2903998090 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Fluoroboric acid-->2,3-Dichlorofluorobenzene-->2,3-DIFLUOROCHLOROBENZENE-->1-BROMO-2,6-DICHLOROBENZENE-->2-Chloro-1,3-difluorobenzene-->3-CHLORO-2-FLUORONITROBENZENE-->1,2-Difluorobenzene-->3,5-dichloro-4-fluoroaniline-->3,4,5-Trichloronitrobenzene-->3,5-Dichloro-4-fluoronitrobenzene-->2,6-Dichloroaniline-->1,2-Dichlorobenzene-->2,3-Dichloronitrobenzene-->1,2,3-Trichlorobenzene | [Preparation Products]
1,2,3-Trifluorobenzene-->Acetic acid, 2-(2,3,4-trifluorophenoxy)- |
| Hazard Information | Back Directory | [Chemical Properties]
slightly beige transparent crystals | [Synthesis]
The general procedure for the synthesis of 2,6-dichlorofluorobenzene from 3-chloro-2-fluoronitrobenzene is as follows: In a 250 ml four-necked flask, 240 g (1.368 mol) of 3-chloro-2-fluoronitrobenzene was added and the temperature was raised to 180°C. Dry chlorine gas was passed through the flask, and the temperature of the reaction was controlled to be between 180 and 190°C. The reaction was carried out by distillation. Distillation was carried out during the reaction for 8 to 10 hours. The fractions are collected and sequentially washed with water and alkali to a weak base. The organic phase was separated and subjected to vacuum distillation, resulting in 210 g of 2,6-dichlorofluorobenzene with 99.7% purity and 93% yield. | [References]
[1] Patent: CN102249881, 2016, B. Location in patent: Paragraph 0015; 0050-0051 |
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