| Identification | More | [Name]
Oxyclozanide | [CAS]
2277-92-1 | [Synonyms]
2,3,5-TRICHLORO-N-(3,5-DICHLORO-2-HYDROXYPHENYL)-6-HYDROXYBENZAMIDE
3,3',5,5',6-PENTACHLORO-2'-HYDROXYSALICYLANILIDE
OXYCLOZAMIDE
OXYCLOZANIDE
2,2’-dihydroxy-3,3’,5,5’,6-pentachloro-benzanilid
2,2’-dihydroxy-3,3’,5,5’,6-pentachlorobenzanilide
2,3,5-trichloro-n-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxy-benzamid
3,3’,5,5’,6-pentachloro-2,2’-dihydroxybenzanilide
3,3’,5,5’,6-pentachloro-2’-hydroxy-salicylanilid
3,5,6,3’,5’-pentachloro-2,2’-dihydroxybenzanilide
diplin
ici46638
oxyclozanid
zanil
OXYCLOZANIDE BPV
BPV OXYCLOZANIDE BPV
Oxycloxanide
OXYCLOZANIDE B.P
Benzamide, 2,3,5-trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxy-
3,3μ,5,5μ,6-Pentachloro-2μ-hydroxysalicylanilide, 2,3,5-Trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide | [EINECS(EC#)]
218-904-0 | [Molecular Formula]
C13H6Cl5NO3 | [MDL Number]
MFCD00864507 | [Molecular Weight]
401.46 | [MOL File]
2277-92-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
77-81C | [Boiling point ]
215C | [density ]
1.6274 (rough estimate) | [refractive index ]
1.6200 (estimate) | [storage temp. ]
0-6°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
neat | [pka]
5.07±0.50(Predicted) | [color ]
White to off-white | [Water Solubility ]
29mg/L(25 ºC) | [InChI]
InChI=1S/C13H6Cl5NO3/c14-4-1-6(16)11(20)8(2-4)19-13(22)9-10(18)5(15)3-7(17)12(9)21/h1-3,20-21H,(H,19,22) | [InChIKey]
JYWIYHUXVMAGLG-UHFFFAOYSA-N | [SMILES]
C(NC1=CC(Cl)=CC(Cl)=C1O)(=O)C1=C(O)C(Cl)=CC(Cl)=C1Cl | [CAS DataBase Reference]
2277-92-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS07,GHS09 | [Signal word ]
Warning | [Hazard statements ]
H302-H410 | [Precautionary statements ]
P264-P270-P273-P301+P312-P391-P501 | [Hazard Codes ]
Xn;N,N,Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
UN 3077 | [WGK Germany ]
3 | [RTECS ]
CV8576000 |
| Hazard Information | Back Directory | [Uses]
Anthelmintic | [Synthesis]
A preparation method of Oxyclozanide (pentachloroasalamide), which takes 2, 4-dichlorophenol which is easily available in the market as a raw material, and obtains the pentachloroasalamide by nitration, reduction and condensation with 3, 5, 6-trichlorosalicylic acid.
 | [in vivo]
Oxyclozanide (15 mg/kg (sheep), 10 mg/kg (cattle); oral administration) shows antiparasitic effectiveness in sheep and cattle[1].
Oxyclozanide (1500-5000 mg/kg; oral administration, once) induces multiple toxic symptoms in acute toxicity test of rats[2]. | Animal Model: | Healthy male and female Wistar rats (100-150 g)[2] | | Dosage: | 5000, 3690, 2730, 2025 and 1500 mg/kg | | Administration: | Oral administration; 5000, 3690, 2730, 2025 and 1500 mg/kg; once | | Result: | Induced toxic symptoms of pression, rough hair, inappetence and cyanotic lips, limbs and tail. Induced swelling spleen, bleeding spots in the liver and swelling stomachs at high-dose group.
|
| [IC 50]
Schistosome | [storage]
Store at -20°C |
|
| Company Name: |
Aemon Chemical
|
| Telephone: |
0086-755-86198205 |
| Website: |
www.aemonchem.com |
|