| Identification | Back Directory | [Name]
Leonurine hydrochloride | [CAS]
24697-74-3 | [Synonyms]
SCM-198
Leonurin
Leonurine
LEONURINE HCL
Leonurine (SCM-198)
leonurine hydrochloride
4-Guanidinobutyl syringate
4-Guanidino-1-butanol syringate
Leonurine hydrochloride USP/EP/BP
Leonurine Hydrochloride Monohydrate
Syringic acid ζ-guanidinobutyl ester
Leonurine
4-Guanidino-1-butanol syringate
4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate
Leonurine, 98%, from Leonurus artemisia (Laur.) S. Y. Hu F
4-Hydroxy-3,5-dimethoxybenzoic acid 4-guanidinobutyl ester
4-(diaminomethylideneamino)butyl 4-hydroxy-3,5-dimethoxybenzoate
Benzoic acid, 4-hydroxy-3,5-dimethoxy-, 4-[(aminoiminomethyl)amino]butyl ester
4-(diaminomethylideneamino)butyl 4-hydroxy-3,5-dimethoxy-benzoate hydrochloride
3,5-Dimethoxy-4-hydroxy-benzoic acid (4-guanidino)-1-butyl ester Hydrochloride Monohydrate | [EINECS(EC#)]
683-174-6 | [Molecular Formula]
C14H21N3O5 | [MDL Number]
MFCD09839432 | [MOL File]
24697-74-3.mol | [Molecular Weight]
311.33 |
| Chemical Properties | Back Directory | [Melting point ]
238 °C | [Boiling point ]
496.7±55.0 °C(Predicted) | [density ]
1.29±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
DMSO: soluble2mg/mL, clear (warmed) | [form ]
powder | [pka]
8.26±0.25(Predicted) | [color ]
white to beige | [Stability:]
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. | [InChIKey]
WNGSUWLDMZFYNZ-UHFFFAOYSA-N |
| Hazard Information | Back Directory | [Description]
An amorphous alkaloid, leonurine has been obtained from the leaves of Leonurus
sibiricus L. and is characterized as the crystalline hydrochloride hydra te, m.p.
19l-4°C. Hydrolysis yields syringic acid and Q-hydroxybutylguanidine. The
total synthesis of the alkaloid has been achieved, confirming the above structure. | [Uses]
Leonurine is a pseudoalkaloid that has been isolated from Leonotis leonurus. A natural product with antioxidant, anti-inflammatory and cardioprotective properties for the treatment of wild variety of conditions including stroke, cerebral thrombosis and cardiovascular diseases. | [Definition]
ChEBI: Leonurine is a trihydroxybenzoic acid. | [storage]
Store at RT | [References]
Kubota, Nakajima., Nippon Yakubusugaku Zasshi., 163 (1930)
Goto et al., Tetrahedron Lett., 545 (1962)
Total synthesis:
Kishi et al., Tetrahedron Lett., 637 (1968) |
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