| Identification | More | [Name]
4-Chlorovalerophenone | [CAS]
25017-08-7 | [Synonyms]
1-(4-CHLOROPHENYL)-1-PENTANONE
4'-CHLOROPENTANOPHENONE
4-CHLOROVALEROPHENONE
P-CHLOROVALEROPHENONE
TIMTEC-BB SBB005774
1-(4-chlorophenyl)pentan-1-one
1-Pentanone, 1-(4-chlorophenyl)-
1-(4-Chlorophenyl)pentane-1-one
1-Pentanoyl-4-chlorobenzene | [EINECS(EC#)]
246-566-4 | [Molecular Formula]
C11H13ClO | [MDL Number]
MFCD04038938 | [Molecular Weight]
196.67 | [MOL File]
25017-08-7.mol |
| Chemical Properties | Back Directory | [Appearance]
white to yellow crystalline low melting solid | [Melting point ]
29-33 °C | [Boiling point ]
156 °C / 14mmHg | [density ]
1.0753 (rough estimate) | [refractive index ]
1.5364 (estimate) | [Fp ]
30 °C | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
fused solid | [color ]
Off-white to faint yellow | [InChI]
InChI=1S/C11H13ClO/c1-2-3-4-11(13)9-5-7-10(12)8-6-9/h5-8H,2-4H2,1H3 | [InChIKey]
XMUGWCSIQUJOFA-UHFFFAOYSA-N | [SMILES]
C(C1=CC=C(Cl)C=C1)(=O)CCCC | [CAS DataBase Reference]
25017-08-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P280a-P304+P340-P305+P351+P338-P405-P501a | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
3077 | [HS Code ]
29420000 |
| Hazard Information | Back Directory | [Chemical Properties]
white to yellow crystalline low melting solid | [Uses]
4-Chlorovalerophenone is often used as a pharmaceutical intermediate.
| [Synthesis]
A mixture of 346 ml of chlorobenzene and 120 g of valeryl chloride is treated, at room temperature, in the course of 1 hour with portions of aluminium chloride and the mixture is at the same time heated to 70°. The mixture is stirred for a further hour at this temperature and then cooled to 25° and the dark red reaction mixture is poured on to 1,000 g of ice. Concentrated hydrochloric acid is added and the mixture is then extracted with ethyl acetate. The organic extract is washed with 2 N hydrochloric acid, filtered through a diatomaceous earth formulation (Hyflo) and washed with further 2 N hydrochloric acid, twice with water, with a 2 N aqueous solution of sodium carbonate and with water. It is dried over sodium sulphate and filtered and the filtrate is evaporated under reduced pressure. The residue is distilled; 4-Chlorovalerophenone is obtained at 155°-156°/14 mm Hg; the product crystallises and melts at 28°-30°.
|
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
|