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2578-28-1

2578-28-1 Structure

2578-28-1 Structure
IdentificationMore
[Name]

SELENO-DL-METHIONINE
[CAS]

2578-28-1
[Synonyms]

2-AMINO-4-(METHYLSELENO)BUTANOIC ACID
2-AMINO-4-(METHYLSELENO)BUTYRIC ACID
AURORA KA-6143
D,L-2-AMINO-4-(METHYLSELENO)BUTANOIC ACID
DL-SELENOMETHIONINE
SELENO-DL-METHIONINE
SELENOMETHIONINE
(+-)-butanoicaci
DL-SELENOMETHIONINE-13C1 (METHYL-13C) 99
D L-SELENOMETHIONINE 99+%
DL-SELENOMETHIOININE
rac-(2R*)-2-[2-(Methylseleno)ethyl]glycine
[EINECS(EC#)]

215-977-0
[Molecular Formula]

C5H11NO2Se
[MDL Number]

MFCD00063089
[Molecular Weight]

196.11
[MOL File]

2578-28-1.mol
Chemical PropertiesBack Directory
[Appearance]

colorless, faint smelling, glistening powder
[Melting point ]

267-269 °C
[storage temp. ]

−20°C
[solubility ]

0.5 M HCl: 50 mg/mL, clear, colorless
[form ]

Glistening Powder
[color ]

Colorless
[Merck ]

8441
[InChI]

InChI=1S/C5H9NO2SSe/c1-9-3-2-4(6-10)5(7)8/h4H,2-3H2,1H3,(H,7,8)
[InChIKey]

SHQDAFLUPMUAME-UHFFFAOYSA-N
[SMILES]

C(O)(=O)C(CCSC)N=[Se]
[CAS DataBase Reference]

2578-28-1(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

T,N
[Risk Statements ]

R23/25:Toxic by inhalation and if swallowed .
R33:Danger of cumulative effects.
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
[Safety Statements ]

S20/21:When using, do not eat, drink or smoke .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
[RIDADR ]

UN 3283 6.1/PG 2
[WGK Germany ]

3
[RTECS ]

ES7110000
[F ]

10
[HazardClass ]

6.1(a)
[PackingGroup ]

II
[HS Code ]

29319090
Hazard InformationBack Directory
[Hazard]

A poison.
[Chemical Properties]

colorless, faint smelling, glistening powder
[Uses]

Selenization is a common method for protein crystallization, and selenomethionine (SELENO-DL-METHIONINE) is a commonly used reagent in selenomethionine crystallization. In practice, this product is used as a nutrient to culture bacteria, so that the sulfur (S) element in the corresponding proteins produced by bacterial metabolism is replaced by selenium (Se), allowing the crystal form of the protein to be observed using specialized instruments.
[Definition]

ChEBI: Selenomethionine is a selenoamino acid that is the selenium analogue of methionine. It has a role as a plant metabolite. It is a member of selenomethionines and a selenoamino acid.
[Purification Methods]

It crystallises in hexagonal plates from MeOH and H2O. [Klosterman & Painter J Am Chem Soc 69 2009 1949.] The L-isomer [3211-76-5] is purified by dissolving it in H2O, adjusting the pH to 5.5 with aqueous NH3, evaporating to near-dryness, and the residue is washed several times with absolute EtOH till a solid is formed and then recrystallise from Me2CO. It has m 266-268o(dec) [also 275o(dec)], and [] D +18.1o(c 1, N HCl). [Pande et al. J Org Chem 35 1440 1970, Beilstein 4 IV 3216.]
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

DL-Selenomethionine, 99+%(2578-28-1)
[Sigma Aldrich]

2578-28-1(sigmaaldrich)
[TCI AMERICA]

DL-Selenomethionine,>98.0%(T)(2578-28-1)
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3211-76-5 50-81-7 63-68-3