| Identification | More | [Name]
L-(+)-Selenomethionine | [CAS]
3211-76-5 | [Synonyms]
2-AMINO-4-(METHYLSELENO)BUTANOIC ACID
L-(+)-2-AMINO-4-(METHYLSELENO)BUTANOIC ACID
L-(+)-SELENOMETHIONINE
L-SELENOMETHIONINE
(S)-(+)-2-AMINO-4-(METHYLSELENO)BUTANOIC ACID
(S)-2-AMINO-4-(METHYLSELENO)BUTYRIC ACID
SELENO-L-METHIONINE
SELENOMETHIONINE, L-(+)-
SEMET
L(+)-SELENOMETHIONINE 99+% E.E.
(S)-2-AMINO-4-(METHYLSELENYL)BUTYRIC ACID
L(+)-Selenomethionine, ee 99+%, 99+%
Butanoic acid, 2-amino-4-(methylseleno)-, (2S)-
L-SELENOMETHIONINE SELENO-L-METHIONINE L-SE-MET-OH
L-selenomethionine （L-se-Met-OH）
BUTYRICACID,2-AMINO-4-(METHYLSELENYL)-,L-
L-SELENOMETHIONINE 0.5%
L-SELENOMETHIONINE USP
THALLIUM ETHYLSUFATE
(S)-(+)-2-Amino-4-(methylseleno)butanoic acid, (S)-2-Amino-4-(methylseleno)butyric acid, L-Selenomethionine, Seleno-L-methionine | [EINECS(EC#)]
608-705-0 | [Molecular Formula]
C5H11NO2Se | [MDL Number]
MFCD00037210 | [Molecular Weight]
196.11 | [MOL File]
3211-76-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Solid | [Melting point ]
265 °C
| [alpha ]
18 º (c=1, 1N HCl) | [Boiling point ]
320.8±37.0 °C(Predicted) | [refractive index ]
18 ° (C=0.5, 2mol/L HCl) | [storage temp. ]
−20°C
| [solubility ]
H2O: 50 mg/mL
| [form ]
powder
| [pka]
2.26±0.10(Predicted) | [color ]
white to off-white
| [Water Solubility ]
soluble | [Merck ]
8441 | [Cosmetics Ingredients Functions]
ANTIOXIDANT | [InChI]
InChI=1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1 | [InChIKey]
RJFAYQIBOAGBLC-BYPYZUCNSA-N | [SMILES]
C(O)(=O)[C@@H](N)CC[Se]C | [LogP]
0.152 (est) | [CAS DataBase Reference]
3211-76-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
  
GHS06,GHS08,GHS09 | [Signal word ]
Danger | [Hazard statements ]
H301+H331-H373-H410 | [Precautionary statements ]
P260-P301+P330+P331+P310-P304+P340+P311-P403+P233 | [Hazard Codes ]
T,N | [Risk Statements ]
R23/25:Toxic by inhalation and if swallowed .
R33:Danger of cumulative effects.
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S20/21:When using, do not eat, drink or smoke .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN 3283 6.1/PG 2
| [WGK Germany ]
3
| [RTECS ]
EK7713840
| [F ]
10 | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29309090 | [Storage Class]
6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | [Hazard Classifications]
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
STOT RE 2 |
| Hazard Information | Back Directory | [Chemical Properties]
Solid | [Uses]
A compound shown to increase expression of glutathione peroxidase | [Definition]
ChEBI: The L-enantiomer of selenomethionine. | [General Description]
Seleno-L-Methionine (SeMet), an organic form of selenium is found in Cupriavidus metallidurans. | [Biochem/physiol Actions]
Seleno-L-Methionine (SeMet) is capable of repressing atopic dermatitis (AD)-like skin lesions. It can also prevent the expression of total immunoglobulin E (IgE) and interleukin 4 (IL-4). It can cause ecotoxicity as it is absorbed by fish through diet. | [Synthesis]
Under nitrogen protection, 13.75 g of L-homoserine lactone hydrochloride was mixed with 40 mL of N,N-dimethylformamide (DMF) and stirred until completely dissolved. Subsequently, 15.2 g of methyl selenate (CAS:37773-10-7) was dissolved in 20 mL of DMF and slowly added to the above reaction system. The reaction was heated and refluxed for 2 hours. Upon completion of the reaction, the pH of the reaction system was adjusted to 6.0 with aqueous acetic acid and a white solid was precipitated. The resulting solid was dissolved in a mixed solvent of water and ethanol for recrystallization to obtain L-selenomethionine. The total yield of this synthetic route was 72.11%, the chemical purity of the product was greater than 99% and the enantiomeric excess value (ee) was greater than 99%. | [References]
[1] Patent: CN106928110, 2017, A. Location in patent: Paragraph 0028; 0030 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|