| Identification | Back Directory | [Name]
Flutoprazepam | [CAS]
25967-29-7 | [Synonyms]
KB-509
Restar
Restas
KB-509P
ID-1937
Flutoprazepam
Flutoprazepamum
2H-1,4-BENZODIAZEPIN-2-ONE
7-Chloro-1-(cyclopropylMethyl)-5-(2-fluorophenyl)-1H-benzo[e][1,4]diazepin-2(3H)-one
7-Chloro-1-(cyclopropylmethyl)-5-(2-fluorophenyl)-1，3-dihydro-2H-1，4-benzodiazepin-2-one
2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-1-(CYCLOPROPYLMETHYL)-5-(2-FLUOROPHENYL)-1,3-DIHYDRO- | [Molecular Formula]
C19H16ClFN2O | [MDL Number]
MFCD00866972 | [MOL File]
25967-29-7.mol | [Molecular Weight]
342.79 |
| Chemical Properties | Back Directory | [Melting point ]
118-122° | [Boiling point ]
539.3±50.0 °C(Predicted) | [density ]
1.2683 (estimate) | [solubility ]
DMF: 30 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 25 mg/ml; Ethanol: 1 mg/ml | [form ]
A crystalline solid | [pka]
1.93±0.35(Predicted) |
| Hazard Information | Back Directory | [Description]
Flutoprazepam is a benzodiazepine anti-anxiety
agent, somewhat longer acting and more potent
than diazepam. | [Originator]
Sumitomo (Japan) | [Uses]
Flutoprazepam, is a drug of a benzodiazepine class. It has shown to have muscle relaxant properties almost equivalent to Diazepam (D416855), however having more powerful sedative, hypnotic, anxiolytic and anticonvulsant effects. | [Definition]
ChEBI: Flutoprazepam is an organic molecular entity. | [Brand name]
RESTAS |
| Safety Data | Back Directory | [Toxicity]
LD50 in male, female mice, rats (mg/kg): 2640, 2430, 13760, 10060 orally; 2400, 2110, 2460, 2230 i.p.; >5000 s.c. all species (Takebe) |
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