| Identification | More | [Name]
7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one | [CAS]
2886-65-9 | [Synonyms]
5-(2-FLUOROPHENYL)-7-CHLORO-1,4-BENZODIAZEPIN-2-ONE
7-CHLORO-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-1,4-BENZODIAZEPIN-2-ONE
7-CHLORO-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE
7-CHLORO-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE
DESALKYLFLURAZEPAM
NORFLUDIAZEPAM
1,3-dihydro-7-chloro-5-(2-fluorophenyl)-2h-4-benzodiazepin-2-one
2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(2-fluorophenyl)-
2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-
2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-fluorophenyl)-1,3-dihydro-
7-chloro-5-(o-fluorophenyl)-1,3-dihydro-2h-4-benzodiazepin-2-one
cm7116
Dealkylflurazepam
Descarbethoxyloflazepate
Flurazepam M (des-alkyl)
Flurazepam M (N-1-des-alkyl)
Flurazepam, des-alkyl
N-1-desalkyl-flurazepam
N-Desalkyl-2-oxoquazepam
N-Desalkylflurazepam | [EINECS(EC#)]
220-748-3 | [Molecular Formula]
C15H10ClFN2O | [MDL Number]
MFCD00083443 | [Molecular Weight]
288.7 | [MOL File]
2886-65-9.mol |
| Chemical Properties | Back Directory | [Appearance]
Light Yellow Solid | [Melting point ]
204-206°C | [Boiling point ]
454.0±45.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [Fp ]
9℃ | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
A neat solid | [pka]
11.55±0.70(Predicted) | [Usage]
The major human metabolite of flurazepam. This is a controlled drug precursor therefore a liscence may be required for purchase | [InChI]
InChI=1S/C15H10ClFN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20) | [InChIKey]
UVCOILFBWYKHHB-UHFFFAOYSA-N | [SMILES]
N1C2=CC=C(Cl)C=C2C(C2=CC=CC=C2F)=NCC1=O | [CAS DataBase Reference]
2886-65-9(CAS DataBase Reference) | [NIST Chemistry Reference]
Norfludiazepam(2886-65-9) |
| Safety Data | Back Directory | [Hazard Codes ]
F,T | [Risk Statements ]
11-23/24/25-39/23/24/25 | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [RIDADR ]
UN1230 - class 3 - PG 2 - Methanol, solution | [WGK Germany ]
2
| [RTECS ]
DF2370100
| [HS Code ]
2933997500 |
| Hazard Information | Back Directory | [Description]
Desalkylflurazepam (Item No. 18484) is an analytical reference material that is structurally categorized as a benzodiazepine. It is an active metabolite of several benzodiazepines, including flurazepam (Item No. 18160), flutoprazepam, fludiazepam, midazolam, and quazepam. Desalkylflurazepam inhibits L-type voltage-gated calcium channels (Cav; IC50s = 55 and 37 μM for Cav1.2 and 1.3, respectively) by positively modulating GABAA receptors.1 It can be detected in urine, serum, and meconium by LC-MS/MS.2 This product is intended for research and forensic applications. | [Chemical Properties]
Light Yellow Solid | [Uses]
The major human metabolite of Flurazepam.
Controlled substance.
| [Uses]
The major human metabolite of flurazepam. This is a controlled drug precursor therefore a liscence may be required for purchase | [Definition]
ChEBI: Desalkylflurazepam is a benzodiazepine. | [General Description]
N-Desalkylflurazepam (also known as norflurazepam, 2886-65-9) is a benzodiazepine analog and an active metabolite of several other benzodiazepine drugs including flurazepam, flutoprazepam, fludiazepam, midazolam, flutazolam, quazepam, and ethyl loflazepate. It is long-acting, prone to accumulation, and binds unselectively to the various benzodiazepine receptor subtypes. It has been sold as a designer drug from 2016 onward. | [Mode of action]
N-Desalkylflurazepam is a benzodiazepine analog and an active metabolite of several other benzodiazepine drugs including flurazepam, flutoprazepam, fludiazepam, midazolam, flutazolam, quazepam, and ethyl loflazepate. It is long-acting, prone to accumulation, and binds unselectively to the various benzodiazepine receptor subtypes. It has been sold as a designer drug from 2016 onward. |
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