| Identification | More | [Name]
1,2-(Methylenedioxy)-4-nitrobenzene | [CAS]
2620-44-2 | [Synonyms]
1,2-(METHYLENEDIOXY)-4-NITROBENZENE
3,4-METHYLENEDIOXYNITROBENZENE
5-NITRO-1,3-BENZODIOXOLE
3,4-(Methylenedioxy)-1-nitrobenzene
5-nitro-3-benzodioxole
5-Nitrobenzodioxole
Benzene, 1,2-(methylenedioxy)-4-nitro-
Methylenedioxynitrobenzene
5-Nitro-1,3-benzodioxole~4-Nitro-1,2-(methylenedioxy)benzene
Nitro-1,2-Methylene Dioxybenzene
4-Nitrobenzodioxole
forOxolinicacid
4-nitro-1,2-(methylenedioxy)benzene
3,4-(METHYLENEDIOXY)-4-NITROBENZENE
3,4-Methylenedioxynitrobenzene 98%
NITROBENZODIOXOLE
1,2-Methylenedioxy-4-nitrobenzene, 98+%
1,3-Benzodioxole, 5-nitro-
3,4-Methylenebisoxy-1-nitrobenzene | [EINECS(EC#)]
220-055-6 | [Molecular Formula]
C7H5NO4 | [MDL Number]
MFCD00005824 | [Molecular Weight]
167.12 | [MOL File]
2620-44-2.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow fine crystalline powder | [Melting point ]
146-148 °C (lit.) | [Boiling point ]
295.67°C (rough estimate) | [density ]
1.5216 (rough estimate) | [refractive index ]
1.6280 (estimate) | [Fp ]
289 °F
| [storage temp. ]
Store at room temperature | [solubility ]
acetone: soluble2.5%, clear to slightly hazy, yellow | [form ]
powder to crystal | [color ]
Light yellow to Yellow to Orange | [BRN ]
169063 | [InChI]
1S/C7H5NO4/c9-8(10)5-1-2-6-7(3-5)12-4-11-6/h1-3H,4H2 | [InChIKey]
SNWQAKNKGGOVMO-UHFFFAOYSA-N | [SMILES]
[O-][N+](=O)c1ccc2OCOc2c1 | [CAS DataBase Reference]
2620-44-2(CAS DataBase Reference) | [NIST Chemistry Reference]
1,3-Benzodioxole, 5-nitro-(2620-44-2) | [EPA Substance Registry System]
2620-44-2(EPA Substance) |
| Questions And Answer | Back Directory | [Synthesis]
In air, benzo[d][1,3]dioxane 1a (0.5 mmol, 61 mg), I2O5 (2.5 mmol, 835 mg), NaNO2 (2.5 mmol, 173 mg), 2 mL CH3NO2 and 0.1 mL water were added sequentially to a 10 mL sealed pressure-resistant tube. The reaction was carried out at 15 °C with vigorous magnetic stirring for 2 h. The reaction was monitored by TLC. After the reaction was complete, anhydrous Na₂SO₃ was added to quench the reaction. First, 15 mL of saturated Na₂SO₃ was added to the reaction solution. The aqueous phase was washed with 15 mL of CH₂Cl₂, the organic phases were combined, dried over anhydrous Na₂SO₄, filtered, and the solvent in the filtrate was removed under reduced pressure. Column chromatography (ethyl acetate: petroleum ether = 1:5) was used to separate 70 mg of a pale yellow solid, 1,2-methylenedioxy-4-nitrobenzene, in 84% yield. |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302+H312+H332 | [Precautionary statements ]
P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [HS Code ]
29329990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Chemical Properties]
yellow fine crystalline powder | [Uses]
1,2-(Methylenedioxy)-4-nitrobenzene undergoes continuous hydrogenation in supercritical CO2 with poly siloxane-supported noble metal catalyst in small flow reactor. | [Synthesis Reference(s)]
Journal of Heterocyclic Chemistry, 28, p. 625, 1991 DOI: 10.1002/jhet.5570280316
Tetrahedron, 64, p. 4999, 2008 DOI: 10.1016/j.tet.2008.03.085 | [General Description]
1,2-(Methylenedioxy)-4-nitrobenzene undergoes continuous hydrogenation in supercritical CO2 with poly siloxane-supported noble metal catalyst in small flow reactor. |
|
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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Alfa Aesar
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400-6106006 |
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http://chemicals.thermofisher.cn |
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Energy Chemical
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www.energy-chemical.com |
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China Langchem Inc.
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0086-21-58956006 |
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Maya High Purity Chemicals
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Modachem Shanghai Co., Ltd
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+86 (0)21 51320687 51371369 1744605818 |
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