| Identification | More | [Name]
L-Cyclohexylalanine | [CAS]
27527-05-5 | [Synonyms]
2-AMINO-3-CYCLOHEXYLPROPANOIC ACID
3-CYCLOHEXYL-L-ALANINE
3-CYCLOHEXYL-L-ALANINE HYDROCHLORIDE
3-CYCLOHEXYL-L-ALANINE HYDROCHLORIDE SALT
BETA-CYCLOHEXYL-ALANINE HCL
BETA-CYCLOHEXYL-L-ALANINE
BETA-CYCLOHEXYL-L-ALANINE HYDROCHLORIDE
H-BETA-CYCLOHEXYL-ALA-OH HCL
H-CHA-OH
H-CHA-OH HCL
HEXAHYDRO-L-PHENYLALANINE HCL
HEXAHYDRO-L-PHENYLALANINE HYDROCHLORIDE
H-L-CHA-OH
H-PHE(HEXAHYDRO)-OH HCL
L-2-AMINO-3-CYCLOHEXYL-PROPIONIC ACID
L-2-AMINO-3-CYCLOHEXYL-PROPIONIC ACID HYDROCHLORIDE
L-2-AMINO-3-HEXAHYDROPHENYL-PROPIONIC ACID HYDROCHLORIDE
L-3-CYCLOHEXYL-ALANINE
L-3-CYCLOHEXYLALANINE HYDROCHLORIDE SALT
L-CHA | [EINECS(EC#)]
1308068-626-2 | [Molecular Formula]
C9H17NO2 | [MDL Number]
MFCD00190861 | [Molecular Weight]
171.24 | [MOL File]
27527-05-5.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
322 °C | [Boiling point ]
307.1±25.0 °C(Predicted) | [density ]
1.075±0.06 g/cm3(Predicted) | [storage temp. ]
Store at 0°C | [form ]
Solid | [pka]
2.33±0.10(Predicted) | [color ]
White to off-white | [InChI]
InChI=1/C9H17NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h7-8H,1-6,10H2,(H,11,12)/t8-/s3 | [InChIKey]
ORQXBVXKBGUSBA-SBYBRXNCNA-N | [SMILES]
C1(CCCCC1)C[C@H](N)C(=O)O |&1:7,r| | [CAS DataBase Reference]
27527-05-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
10 | [Hazard Note ]
Irritant | [HS Code ]
2922498590 |
| Questions And Answer | Back Directory | [Description]
L-Cyclohexylalanine is a kind of amino acid analog. It has some pharmacological effects. Study has shown that some of its derivatives exhibit potent bactericidal activity against drug-resistant gram-positive pathogens. Its derivatives can also act as dipeptidyl peptidase-IV inhibitor, which can be used for the treatment or prevention of diabetes.
| [References]
http://nizetlab.ucsd.edu/Publications/CombinatorialLibrary.pdf
Duffy, Joseph L, et al. "Cyclohexylalanine derivatives as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes." CN, CN 1960990 A. 2007.
Aarstad, K, T. L. Zimmer, and S. G. Laland. "The fidelity of gramicidin S synthetase." European Journal of Biochemistry 112.2(1980):335-338.
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