| Identification | More | [Name]
5-METHOXY-DL-TRYPTOPHAN | [CAS]
28052-84-8 | [Synonyms]
5-METHOXY-DL-TRYPTOPHAN
DL-2-AMINO-3-(5-METHOXYINDOLYL)PROPIONIC ACID
DL-5-METHOXYTRYPTOPHAN
DL-AMINO-3-(5-METHOXYINDOLYL)PROPIONIC ACID
H-5-MEO-DL-TRP-OH
5-Methoxy-DL-tryptophan, (SR)-2-Amino-3-(5-methoxyindolyl)propionic acid, 98%
H-Trp(5-OMe)-OH | [EINECS(EC#)]
248-800-0 | [Molecular Formula]
C12H14N2O3 | [MDL Number]
MFCD00005650 | [Molecular Weight]
234.25 | [MOL File]
28052-84-8.mol |
| Chemical Properties | Back Directory | [Appearance]
off-white powder | [Melting point ]
258-261 °C (dec.)(lit.) | [Boiling point ]
376.57°C (rough estimate) | [density ]
1.1923 (rough estimate) | [refractive index ]
1.6660 (estimate) | [storage temp. ]
−20°C
| [solubility ]
DMSO: 1 mg/ml; PBS (pH 7.2): 1 mg/ml | [form ]
crystalline
| [color ]
Light yellow to yellow | [BRN ]
26781 | [Major Application]
peptide synthesis | [InChI]
1S/C12H14N2O3/c1-17-8-2-3-11-9(5-8)7(6-14-11)4-10(13)12(15)16/h2-3,5-6,10,14H,4,13H2,1H3,(H,15,16) | [InChIKey]
KVNPSKDDJARYKK-UHFFFAOYSA-N | [SMILES]
COc1ccc2[nH]cc(CC(N)C(O)=O)c2c1 | [CAS DataBase Reference]
28052-84-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HazardClass ]
IRRITANT | [HS Code ]
29339900 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
off-white powder | [Uses]
5-Methoxy-DL-tryptophan is a molecule produced by endothelial cells to modulate inflammatory responses and protect against systemic inflammation. It can also suppress lipopolysaccharide-induced inflammatory responses and signaling in macrophages and endotoxemic lung tissues. | [Definition]
ChEBI: 5-Methoxy-DL-tryptophan is a member of tryptamines. It is functionally related to a serotonin. | [Biochem/physiol Actions]
5-Methoxy-DL-tryptophan is an amino acid derivative. | [in vivo]
5-Methoxy-DL-tryptophan (23.5 mg/kg, i.p., twice a week, 12-20 weeks) attenuates ARS staining of the aortic arch region in a mouse model of atherosclerosis and atherosclerotic calcification[1].
| [IC 50]
IL-6 | [storage]
Store at -20°C |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|