| Identification | Back Directory | [Name]
Uridine 5-oxyacetic acid | [CAS]
28144-25-4 | [Synonyms]
Uridine 5-oxyacetic acid
uridin-5-yloxyacetic acid
2-{3-[ACETYL(METHYL)AMINO]-2,4,6-TRIIODOPHENOXY}PROPANOIC ACID
2-((1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)oxy)acetic acid | [Molecular Formula]
C11H12N2O9 | [MOL File]
28144-25-4.mol | [Molecular Weight]
316.221 |
| Hazard Information | Back Directory | [Uses]
Uridine-5-oxyacetic acid is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [Definition]
ChEBI:Uridin-5-yloxyacetic acid is a derivative of uridine, bearing an additional carboxymethoxy substituent at position 5 on the uracil ring. It is a member of uridines and a monocarboxylic acid. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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