| Identification | More | [Name]
N-Methylolchloroacetamide | [CAS]
2832-19-1 | [Synonyms]
2-CHLORO-N-(HYDROXYMETHYL)ACETAMIDE
N1-HYDROXYMETHYL-2-CHLOROACETAMIDE
N-HYDROXYMETHYL-2-CHLOROACETAMIDE
N-HYDROXYMETHYLCHLOROACETAMIDE
N-METHYLOLCHLOROACETAMIDE
TIMTEC-BB SBB004273
2-chloro-N-(hydroxymethyl)acetamid
2-chloro-n-(hydroxymethyl)-acetamid
2-chloro-n-hydroxymethyl-acetamid
chloracetamide-n-metholol
n-methylol-chloracetamide
N-Hydromethyl-2-Chloroacetamide
Acetamide, 2-chloro-N-(hydroxymethyl)-
2-Chioro-N-hydroxymethylacetamide
METHYLOLCHLOROACETAMIDE
CHLOROACETAMIDEN-METHYLOL
CHLOROHYDROXYMETHYLACETAMIDE
N-(Hydroxymethyl)-2-chloracetamide
N-Methylol-2-chloroacetamide
Grotan HD | [EINECS(EC#)]
220-598-9 | [Molecular Formula]
C3H6ClNO2 | [MDL Number]
MFCD00021961 | [Molecular Weight]
123.54 | [MOL File]
2832-19-1.mol |
| Chemical Properties | Back Directory | [Appearance]
White or almost white crystalline powder | [Melting point ]
100-105 °C(lit.) | [Boiling point ]
374.0±27.0 °C(Predicted) | [density ]
1.2776 (rough estimate) | [refractive index ]
1.5000 (estimate) | [storage temp. ]
0-6°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
12.63±0.46(Predicted) | [color ]
White to Off-White | [Water Solubility ]
Very soluble in water. Poorly soluble in aliphatic hydrocarbons. | [Sensitive ]
Hygroscopic | [BRN ]
1811765 | [InChI]
InChI=1S/C3H6ClNO2/c4-1-3(7)5-2-6/h6H,1-2H2,(H,5,7) | [InChIKey]
TXNSZCSYBXHETP-UHFFFAOYSA-N | [SMILES]
C(NCO)(=O)CCl | [CAS DataBase Reference]
2832-19-1(CAS DataBase Reference) | [EPA Substance Registry System]
2832-19-1(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns.
R43:May cause sensitization by skin contact.
R40:Limited evidence of a carcinogenic effect.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S27:Take off immediately all contaminated clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 3261 8/PG 2
| [WGK Germany ]
3
| [RTECS ]
AB5733000
| [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
Ⅱ | [HS Code ]
29241990 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Eye Dam. 1
Skin Corr. 1B |
| Hazard Information | Back Directory | [Chemical Properties]
White or almost white crystalline powder | [Uses]
2-Chloro-N-(hydroxymethyl)acetamide (N-hydroxymethylchloroacetamide) may be used as a reagent in the synthesis of 1-(aminomethyl)-2-methoxynaphthalene hydrochloride and as a amidomethylating reagent for N,N-dialkylanilines (Tscherniac-Einhorn reaction). | [Uses]
An organic building block. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals. As dyestuff intermediate . | [Uses]
N-Methylolchloro-acetamide is a preservative in cooling fluids and cosmetics. | [General Description]
2-Chloro-N-(hydroxymethyl)acetamide (N-methylolchloracetamide) is a N-hydroxymethyl derivative of chloroacetamide. One of the method reported for its synthesis is by the reaction of 2-chloracetamide with formaldehyde. It has been reported to be a formaldehyde releaser and an infrequent sensitizer to formaldehyde contact allergy. Influence of short and prolonged exposure of 2-chloro-N-(hydroxymethyl)acetamide (as formaldehyde donor/releaser) on lymph node responses has been investigated. It has high biocide action and is utilized as preservative. |
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