ChemicalBook--->CAS DataBase List--->2922-28-3

2922-28-3

2922-28-3 Structure

2922-28-3 Structure
IdentificationMore
[Name]

Adenine hydrochloride
[CAS]

2922-28-3
[Synonyms]

1H-Purin-6-amine monohydrochloride
6-AMINOPURINE HCL
6-AMINOPURINE HYDROCHLORIDE
ADENINE HCL
ADENINE HYDROCHLORIDE
ADENINE MONOHYDROCHLORIDE
ADENINIUM CHLORIDE
TIMTEC-BB SBB003841
6-Aminopurine hydrochloride anhydrous
Adenine hydrochloride anhydrous
Adenine hydrochloride, 98%, cont. up to ca 5% water
[EINECS(EC#)]

220-867-0
[Molecular Formula]

C5H6ClN5
[MDL Number]

MFCD00075782
[Molecular Weight]

171.59
[MOL File]

2922-28-3.mol
Chemical PropertiesBack Directory
[Appearance]

white to light yellow crystal powder
[Melting point ]

~285 °C (dec.)
[storage temp. ]

Inert atmosphere,Room Temperature
[solubility ]

H2O: 50 mg/mL
[form ]

powder
[color ]

White to Off-White
[Merck ]

152
[BRN ]

4009585
[CAS DataBase Reference]

2922-28-3(CAS DataBase Reference)
[EPA Substance Registry System]

2922-28-3(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xn,Xi
[Risk Statements ]

R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

3
[F ]

3-8
[TSCA ]

Yes
[HS Code ]

29335990
Hazard InformationBack Directory
[Chemical Properties]

white to light yellow crystal powder
[Uses]

Adenine hydrochloride hydrate has been used:
  • As a component of FAD cell culture media
  • In maintaining organotypic cultures for recreating stratified epithelium from primary cell cultures
  • In limbal-corneal epithelial culturing and keratinocytes

[Uses]

Adenine is a purine nucleobase with a wide range of chemical and biochemical roles in vivo and in vitro. It is a regulatory molecule and a component of DNA, RNA, cofactors (NAD, FAD) and signaling molecules (cAMP).
[Biological Activity]

adenine hcl, a purine derivative and a nucleobase, plays crucial roles in substantial biochemistry processes in vivo, including cellular respiration, formation of the energy-rich adenosine triphosphate (atp), the cofactors nicotinamide adenine dinucleotide (nad) and flavin adenine dinucleotide (fad) as well as protein synthesis. in addition, adenine hcl also serves as a chemical component of dna and rna. adenosine triphosphate is used in cellular metabolism as one of the basic methods of transferring chemical energy between chemical reactions. [1]
[in vitro]

the cyto-protective effect of adenosine was measured using an in vitro model of acute tubular necrosis in rat kidney tubular cells. the finding suggested that adenosine at the concentration of 100 m could significantly decrease cellular injury. the ec50 value of adenosine was detected to be 14 m. [2]
[in vivo]

a study was performed to investigate the effects of dietary adenine on fatty liver induced by orotic acid (oa) in rats. 1% oa-supplemented diets with/ without 0.25% adenine was administered to rats for 10 days. enzyme assay kits were then applied to measure serum lipid profiles of tested rats, such as liver lipid concentrations in different treatment groups. moreover, the activities of fatty acid synthase (fas) and fatty acid β-oxidation were also detected. the findings suggested that addition of adenine to the diet offset the effect of oa and reversed promotion of liver tg content to basal level. administration of adenine also inhibited fas activities in rat liver. in conclusion, the ameliorating of fatty liver in adenine-treated rats was associated with the reduction of fas activities accompanied with the increase of mitochondrial fatty acid β-oxidation and the promotion of serum lipid secretion from the hepatic tissue into the bloodstream. [1]
[storage]

Store at -20°C
[References]

[1]buang y. dietary adenine alleviates fatty liver induced by orotic acid. indo. j. chem. 2010; 10 (3): 363 - 369.
[2] módis k, ger d, nagy n, szoleczky p, tóth zd and szabó c. cytoprotective effects of adenosine and inosine in an in vitro model of acute tubular necrosis. br j pharmacol. 2009 nov; 158(6): 1565–8.
Spectrum DetailBack Directory
[Spectrum Detail]

Adenine hydrochloride(2922-28-3)MS
Adenine hydrochloride(2922-28-3)1HNMR
Adenine hydrochloride(2922-28-3)13CNMR
Adenine hydrochloride(2922-28-3)IR1
Adenine hydrochloride(2922-28-3)IR2
Adenine hydrochloride(2922-28-3)Raman
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

Adenine hydrochloride, 98+%, cont. up to ca 5% water(2922-28-3)
[Sigma Aldrich]

2922-28-3(sigmaaldrich)
[TCI AMERICA]

Adenine Hydrochloride  Hemihydrate,>98.0%(T)(2922-28-3)
2922-28-3 suppliers list
Company Name: Hebei Mojin Biotechnology Co., Ltd
Tel: +8613288715578 , +8613288715578
Website: www.mojinchemical.com
Company Name: Hebei Guanlang Biotechnology Co,.LTD
Tel: +8619930503252 , +8619930503252
Website: https://www.chemicalbook.com/manufacturer/hebei-crovell-biotech-455/
Company Name: Hebei Duling International Trade Co. LTD
Tel: +8618032673083 , +8618032673083
Website: www.chemicalbook.com/showsupplierproductslist1283525/0.htm
Company Name: Capot Chemical Co.,Ltd.
Tel: 571-85586718 +8613336195806 , +8613336195806
Website: http://www.capotchem.com
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512 , +86-19937530512
Website: https://www.tianfuchem.com/
Company Name: Anhui Royal Chemical Co., Ltd.
Tel: +86-25-86655873 +8613962173137 , +8613962173137
Website: http://www.royal-chem.com
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: +86-0551-65418679 +86-18949832763 , +86-18949832763
Website: http://www.tnjchem.com
Company Name: career henan chemical co
Tel: +86-0371-86658258
Website: https://www.coreychem.com/
Company Name: Hebei Guanlang Biotechnology Co., Ltd.
Tel: +86-19930503282 , +86-19930503282
Website: https://www.chemicalbook.com/manufacturer/crovell/
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Website: www.chemicalbook.com/ShowSupplierProductsList1549548/0.htm
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-023-61398051 +8613650506873 , +8613650506873
Website: http://www.chemdad.com/
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427 , +8618523575427
Website: http://www.conier.com/
Company Name: Zhengzhou Alfa Chemical Co.,Ltd
Tel: +8618530059196 , +8618530059196
Website: https://www.chemicalbook.com/manufacturer/zhengzhou-alfa-chemical-276/
Company Name: SIMAGCHEM CORP
Tel: +86-13806087780 , +86-13806087780
Website: http://www.simagchem.com/
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: 0551-65418671
Website: https://www.tnjchem.com
Company Name: ANHUI WITOP BIOTECH CO., LTD
Tel: +8615255079626 , +8615255079626
Website: www.chemicalbook.com/showsupplierproductslist418627/0_en.htm
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250 , +86-15129568250
Website: www.dideu.com
Company Name: AFINE CHEMICALS LIMITED
Tel: 0571-85134551
Website: www.afinechem.com/index.html
Tags:2922-28-3 Related Product Information
106-20-7 62-53-3 321-30-2 70700-30-0 73-24-5 52175-10-7 1839-18-5 58-61-7 119413-54-6 1214-39-7 146-77-0 2922-28-3