| Identification | More | [Name]
4-(Hydroxymethyl)benzoic acid | [CAS]
3006-96-0 | [Synonyms]
4-CARBOXYBENZYL ALCOHOL
4-HYDROXYMETHYLBENZOIC ACID
HMBA
HMBA LINKER
RARECHEM AL BO 1443
HMBA LINKER,4-HYDROXYTHYLBENZOIC ACID
Hydroxymethylbenzoicacid
4-Hydroxythylbenzoic acid
hb linker
Benzoic acid, 4-(hydroxymethyl)-
4-(HYDROXYMETHYL)BENZOIC ACID HMBA LINKER 98%
4-(HYDROXYMETHYL)BENZOIC ACID (HMBA LINKER)
4-(Hydroxymethyl)benzoic acid, 98+% | [EINECS(EC#)]
628-233-9 | [Molecular Formula]
C8H8O3 | [MDL Number]
MFCD00017598 | [Molecular Weight]
152.15 | [MOL File]
3006-96-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
182-185 °C (lit.) | [Boiling point ]
140-150 °C(Press: 9 Torr) | [density ]
1.314±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
DMSO, Methanol | [form ]
Coarse Fibers | [pka]
4.16±0.10(Predicted) | [color ]
White | [BRN ]
2690023 | [InChI]
InChI=1S/C8H8O3/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4,9H,5H2,(H,10,11) | [InChIKey]
WWYFPDXEIFBNKE-UHFFFAOYSA-N | [SMILES]
C(O)(=O)C1=CC=C(CO)C=C1 | [LogP]
0.930 | [CAS DataBase Reference]
3006-96-0(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white solid | [Uses]
4-(Hydroxymethyl)benzoic Acid is an intermediate in the synthesis of Eprosartan (E590100), a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists used as an antihypertensive age
nt. | [Uses]
This linkage reagent for SPPS is essentially acid stable. It is useful in combination with Fmoc-amino acids. Its peptide esters are usually cleaved by basic or nucleophilic reagents, especially by ammonia in the preparation of peptide amides. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 107, p. 1365, 1985 DOI: 10.1021/ja00291a042 | [reaction suitability]
reagent type: linker |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|