| Identification | More | [Name]
4-(Hydroxymethyl)phenoxyacetic acid | [CAS]
68858-21-9 | [Synonyms]
4-(HYDROXYMETHYL)PHENOXYACETIC ACID
HMP
HMPA
HMPA LINKER
HMP LINKER
HPA LINKER
P-(HYDROXYMETHYL)PHENOXYACETIC ACID
HMP LINKER,4-(HYDROXYMETHYL) PHENOXYACETIC ACID
HMP Linker Synonyms:4-(Hydroxymethyl)Phenoxyacetic Acid
Fmoc-SCAL-linker (safety-catch linker for solid phase synthesis)
4-(HYDROXYMETHYL)PHENOXYACETIC ACID HMP LINKER 99+%
HMP LINKER, 99% MIN.
4-(Hydroxymethyl)phenoxyacetic acid, 98+% | [EINECS(EC#)]
677-017-0 | [Molecular Formula]
C9H10O4 | [MDL Number]
MFCD00057827 | [Molecular Weight]
182.17 | [MOL File]
68858-21-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
112-114 °C | [Boiling point ]
378.3±22.0 °C(Predicted) | [density ]
1.316±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Crystalline Powder | [pka]
3.15±0.10(Predicted) | [color ]
Off-white | [biological source]
rabbit | [BRN ]
5260336 | [InChI]
InChI=1S/C9H10O4/c10-5-7-1-3-8(4-2-7)13-6-9(11)12/h1-4,10H,5-6H2,(H,11,12) | [InChIKey]
VUCNQOPCYRJCGQ-UHFFFAOYSA-N | [SMILES]
C(O)(=O)COC1=CC=C(CO)C=C1 | [CAS DataBase Reference]
68858-21-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S27:Take off immediately all contaminated clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
10 | [HS Code ]
29189900 |
| Hazard Information | Back Directory | [Chemical Properties]
Beige powder | [Uses]
4-(Hydroxymethyl)phenoxyacetic acid is a linkage agent used in solid-phase peptide synthesis according to the "FMOC-polyamide" technique.
| [reaction suitability]
reagent type: linker | [Synthesis]
To a mixed solution of tetrahydrofuran ( 12 m L) and water ( 8 m L) of the precursor compound ester ( 312 mg , 1.48 mmol) was added lithium hydroxide (
109 mg, 4.46 mmol) in aqueous solution, the resulting mixture was stirred and reacted at room temperat |
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