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30339-32-3

30339-32-3 Structure

30339-32-3 Structure
IdentificationBack Directory
[Name]

α-phenyl-2-p-tolylethylamine
[CAS]

30339-32-3
[Synonyms]

α-phenyl-2-p-tolylethylamine
(R)-1-phenyl-(2-p-tolyl)ethylamine
(R)-1-phenyl-2-(p-tolyl)ethan-1-amine
Benzeneethanamine, 4-methyl-α-phenyl-, (αR)-
[Molecular Formula]

C15H17N
[MDL Number]

MFCD24391428
[MOL File]

30339-32-3.mol
[Molecular Weight]

211.3
Chemical PropertiesBack Directory
[Boiling point ]

317.8±11.0 °C(Predicted)
[density ]

1.037±0.06 g/cm3(Predicted)
[pka]

8.89±0.10(Predicted)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Nickel-->Benzaldehyde-->4-Chlorobenzaldehyde-->Benzeneacetonitrile-->Biphenyl-->Ethylbenzene-->Diphenylmethane-->Sodium ethylate solution,in ethyl alcohol-->2-Phenylacetophenone-->4-Methylbenzyl chloride
Hazard InformationBack Directory
[Chemical Properties]

This product is white needle-shaped crystals, mp 169.5~170℃, [α]21D=69~69.4°(95% ethanol, C≈0.5), insoluble in water, soluble in organic solvents such as benzene, toluene, ethanol, etc.
[Uses]

(R)-1-Phenyl-2-(p-tolyl)ethylamine is a new resolving base for Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM). Ibuprofen inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.
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