ChemicalBook--->CAS DataBase List--->309-88-6

309-88-6

309-88-6 Structure

309-88-6 Structure
IdentificationMore
[Name]

N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine
[CAS]

309-88-6
[Synonyms]

1,1,2,3,3,3-HEXAFLUORO-1-DIETHYLAMINO-PROPAN
1,1,2,3,3,3-HEXAFLUORO-1-DIETHYLAMINOPROPANE
ISHIKAWA'S REAGENT
MEC-81
N,N-DIETHYL-1,1,2,3,3,3-HEXAFLUOROPROPYLAMINE
SHIKAWA'S REAGENT
Ishikawas
N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine, 40-50% in diglyme
Hexafluoro-1-diethylamino-propane
N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine 97%
N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine97%
ISHIKAWA''S REAGENT: TECH., 90%
DIETHYL-(1,1,2,3,3,3-HEXAFLUOROPROPYL)AMINE
Ishikawa's Reagent [Fluorinating Reagent]
N,N-Diethyl-1,1,2,3,3,3-hexafluoropropan-1-amine
1,1,2,3,3,3-Hexafluoropropyldiethylamine
N,N-Diethyl-1,1,2,3,3,3-hexafluoropropane-1-amine
[EINECS(EC#)]

628-698-8
[Molecular Formula]

C7H11F6N
[MDL Number]

MFCD00054683
[Molecular Weight]

223.16
[MOL File]

309-88-6.mol
Chemical PropertiesBack Directory
[Appearance]

Clear colorless to yellow liquid
[Boiling point ]

56-57 °C (lit.)
[density ]

1.23
[refractive index ]

1.3460
[Fp ]

56-57°C/58mm
[storage temp. ]

Flammables area
[solubility ]

soluble in Acetone,Ether
[form ]

Liquid
[pka]

1.50±0.70(Predicted)
[color ]

Clear colorless to yellow
[Specific Gravity]

1.230
[Merck ]

5108
[InChI]

1S/C7H11F6N/c1-3-14(4-2)7(12,13)5(8)6(9,10)11/h5H,3-4H2,1-2H3
[InChIKey]

BNTFCVMJHBNJAR-UHFFFAOYSA-N
[SMILES]

CCN(CC)C(F)(F)C(F)C(F)(F)F
[CAS DataBase Reference]

309-88-6(CAS DataBase Reference)
[EPA Substance Registry System]

N,N-Diethyl-2H-perfluoropropanamine (309-88-6)
Safety DataBack Directory
[Hazard Codes ]

C
[Risk Statements ]

R10:Flammable.
R34:Causes burns.
[Safety Statements ]

S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
[RIDADR ]

3267
[WGK Germany ]

3
[Hazard Note ]

Corrosive
[HazardClass ]

8
[PackingGroup ]

II
[HS Code ]

29211999
[Storage Class]

3 - Flammable liquids
[Hazard Classifications]

Flam. Liq. 3
Skin Corr. 1B
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine(309-88-6).msds
Hazard InformationBack Directory
[Chemical Properties]

Clear colorless to yellow liquid
[Uses]

Reactant for:
  • Friedel-Crafts type arylation of hydrofluorocarbons
  • Microbial hydroxylation of antibiotics
  • Electrochemical fluorination of trialkylamines and tetraalkylammonium salts
  • Fluorination of pyrethroides

Reactant for synthesis of:
  • γ-Hydroxy-α-fluoro-α-trifluoromethylcarboxamide
  • Florfenicol and thiamphenicol
[Uses]

Demonstrates utility in fluorination.7
[Uses]

Fluorinating agent.
[General Description]

GC analysis includes Et2NCF=CFCF3 (two isomers), both of which are active fluorinating agents.
[Synthesis]

N,N-diethyl-1,1,2,3,3,3-hexafluoropropylamine is prepared as follows: take 600-700 portions of dichloromethane, add 65-85 portions of diethylamine, lower the temperature to -5 ℃ to -25 ℃, pass 110 portions of -165 portions of hexafluoropropylene after the
Spectrum DetailBack Directory
[Spectrum Detail]

N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine(309-88-6)1HNMR
N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine(309-88-6)19FNMR
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine, 90%(309-88-6)
[Alfa Aesar]

Ishikawa's Reagent, 90+%(309-88-6)
[Sigma Aldrich]

309-88-6(sigmaaldrich)
[TCI AMERICA]

Ishikawa's Reagent  [Fluorinating Reagent],>95.0%(T)(309-88-6)
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