| Identification | More | [Name]
Thiocyclam hydrogen oxalate | [CAS]
31895-22-4 | [Synonyms]
FICOLL(R)
NERISECT
THIOCYCLAM HYDROGEN OXALATE
2,3-trithian-5-amine,n,n-dimethyl-ethanedioate(1:1)
5-(dimethylamino)-v-trithianoxalate
5-Di-methylamino-1,2,3-trithiane
5-dimethylamino-1,2,3-trithianehydrogenoxalate
bis(1,2,3-trithiacyclohexyldimethylammonium)oxalate
evisekt
N,N-Dimethyl-1,2,3-trithian-5-amine
n,n-dimethyl-1,2,3-trithian-5-amine,ethanedioate(1:1)
n,n-dimethyl-1,2,3-trithian-5-aminehydrogenoxalate
n,n-dimethyl-1,2,3-trithian-5-ylammoniumhydrogenoxalate
san155
san1551
san155i
thiocyclam(ethanedioate1:1)
thiocyclamhydrogeneoxalate
Evisect
N,N-dimethyl-1,2,3-trithiaxan-5-ylamine oxalate | [EINECS(EC#)]
250-859-2 | [Molecular Formula]
C8H15NO6S2 | [MDL Number]
MFCD00211369 | [Molecular Weight]
285.34 | [MOL File]
31895-22-4.mol |
| Chemical Properties | Back Directory | [vapor pressure ]
5.45 x 10-4 Pa (20 °C) | [Fp ]
130 °C | [storage temp. ]
0-6°C | [form ]
neat | [pka]
3.95 (acid), 7.0 (base) | [Water Solubility ]
16.3 g l-1(20 °C, pH 6.8) | [BRN ]
4771240 | [Major Application]
agriculture
environmental | [InChI]
1S/C5H11NS3.C2H2O4/c1-6(2)5-3-7-9-8-4-5;3-1(4)2(5)6/h5H,3-4H2,1-2H3;(H,3,4)(H,5,6) | [InChIKey]
ICTQUFQQEYSGGJ-UHFFFAOYSA-N | [SMILES]
OC(=O)C(O)=O.CN(C)C1CSSSC1 | [CAS DataBase Reference]
31895-22-4(CAS DataBase Reference) | [EPA Substance Registry System]
31895-22-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,N | [Risk Statements ]
R21/22:Harmful in contact with skin and if swallowed .
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves .
S46:If swallowed, seek medical advice immediately and show this container or label .
S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
2588 | [WGK Germany ]
3 | [RTECS ]
YL8300000 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Dermal
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1 |
| Hazard Information | Back Directory | [Uses]
Thiocyclam (trade name Evisect) is a broad-spectrum nereistoxin analogue insecticide used widely for agricultural applications. | [Uses]
Thiocyclam is used to protect against Lepidoptera, Coleoptera,
some Diptera and Thysanoptera. It is used to control Colorado beetle in
potatoes, Lepidoptera and Coleoptera pest complexes in rape, stem borers
in irrigated rice, corn borers and Tanymecus in maize, weevils and other
Coleoptera in sugar beet, stem borers in sugar cane, Lepidoptera in fruit
trees and leaf miners in vegetables. | [Definition]
ChEBI: An oxalate salt resulting from the formal reaction of equimolar amounts of thiocyclam and oxalic acid. A nicotinic acetylcholine receptor agonist, it was used as a broad-spectrum insecticide. It is not approved for use within the European Union. | [Production Methods]
Thiocyclam oxalate is commercially produced through a multi-step synthesis involving nereistoxin analog chemistry. The industrial synthesis begins with the formation of thiocyclam, a nereistoxin analogue, typically derived from cyclic thioether amines through controlled alkylation and cyclization reactions. This intermediate is then reacted with oxalic acid to form the hydrogen oxalate salt, enhancing its solubility and stability for agricultural formulations. The process requires precise control of temperature, pH, and solvent conditions to ensure high purity and yield of the active ingredient. | [Mechanism of action]
A nereistoxin analogue insecticide. Selective, stomach acting with some contact action. Nicotinic acetylcholine receptor (nAChR) channel blocker. | [Metabolic pathway]
Thiocyclam is a propesticide of the natural product nereistoxin which is a
potent insect neurotoxin isolated from the annelid Lumbviconeveis hetevopoda.
Thiocyclam is rapidly converted into nereistoxin in biological media,
the latter being relatively stable. See the entry for cartap for some further
information on nereistoxin. | [Degradation]
The DT50 value for hydrolysis of thiocyclam hydrogen oxalate at pH 5
is 6 months and at pH values in the range 7-9 is 5-7 days (25 °C). It is
degraded in natural water (not specified) via nereistoxin (2) and its oxide
(3) to compounds of lower molecular weight. The rate of degradation is
increased by irradiation with light. It is degraded by sunlight, the DT50
value being 2-3 days in surface waters (PM). | [Pesticide Type]
Insecticide |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Grader reagent
|
| Telephone: |
18221735425 |
| Website: |
www.shxinping.net |
|