| Identification | More | [Name]
4-Fluoro-2-methylbenzoic acid | [CAS]
321-21-1 | [Synonyms]
4-FLUORO-2-METHYLBENZOIC ACID
RARECHEM AL BE 0506
4-FLUORO-O-TOLUIC ACID
4-Fluoro-2-methylbenzoic acid 99%
4-Fluoro-2-methylbenzoicacid99%
4-FLUORO-2-METHYLBENZOIC ACID 98.0% | [EINECS(EC#)]
206-284-4 | [Molecular Formula]
C8H7FO2 | [MDL Number]
MFCD04115880 | [Molecular Weight]
154.14 | [MOL File]
321-21-1.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
168-172 °C (lit.) | [Boiling point ]
265.6±20.0 °C(Predicted) | [density ]
1.258±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [Water Solubility ]
Insoluble in water | [form ]
powder to crystal | [pka]
3.86±0.25(Predicted) | [color ]
White to Almost white | [InChI]
InChI=1S/C8H7FO2/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4H,1H3,(H,10,11) | [InChIKey]
KDXOONIQRUZGSY-UHFFFAOYSA-N | [SMILES]
C(O)(=O)C1=CC=C(F)C=C1C | [CAS DataBase Reference]
321-21-1(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Preparation]
mixture of 4-fluoro-2-methylbenzonitrile (19.8 g, 150 mmol), KOH (24.3 g, 380 mmol), and water (300 mL) was heated under reflux for two days. The mixture was then acidified with concentrated HCl while cooling. The product was collected by filtration, and the filter cake was washed with water. The solid material was dried after being placed in a hood for several days. 20.8 g (92%) of 4-fluoro-2-methylbenzoic acid was given. 4-fluoro-2-methylbenzoic acid, yield 20.8 g (92%), 1H NMR (300 MHz, DMSO-d6): 2.5 (s, 3H), 7.0–7.2 (m, 2H), 7.9 (t, 1H), 12.8 (b, 1H). |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS05,GHS07 | [Signal word ]
Danger | [Hazard statements ]
H302-H318 | [Precautionary statements ]
P280-P301+P312+P330-P305+P351+P338+P310 | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R41:Risk of serious damage to eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29163990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Dam. 1 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
4-Fluoro-2-methylbenzoic acid can be used in the production of medicines, dye carriers, plasticizers, fragrances and food preservatives. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
|