| Identification | More | [Name]
N-Acetyl-4-piperidone | [CAS]
32161-06-1 | [Synonyms]
1-ACETYL-4-PIPERIDONE
AKOS BBS-00004258
N-ACETYL-4-PIPERIDONE
N-ACETYLPIPERIDIN-4-ONE
1-Acetyl-4-piperidinone
4-Piperidinone, 1-acetyl-
N-Acetylpiperidone
1-Acetyl-4-oxopiperidine
1-Axetyl-4-piperidone
N-Acetyl-4-piperidone, 97%,GC | [EINECS(EC#)]
250-937-6 | [Molecular Formula]
C7H11NO2 | [MDL Number]
MFCD00006190 | [Molecular Weight]
141.17 | [MOL File]
32161-06-1.mol |
| Chemical Properties | Back Directory | [Appearance]
clear orange oily liquid | [Boiling point ]
218 °C(lit.) | [density ]
1.146 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.503(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
Oily Liquid | [pka]
-0.72±0.20(Predicted) | [color ]
Clear orange | [Specific Gravity]
1.16 | [Water Solubility ]
Soluble in water. Insoluble in acetic acid. | [BRN ]
116031 | [InChI]
1S/C7H11NO2/c1-6(9)8-4-2-7(10)3-5-8/h2-5H2,1H3 | [InChIKey]
NNFOVLFUGLWWCL-UHFFFAOYSA-N | [SMILES]
CC(=O)N1CCC(=O)CC1 | [CAS DataBase Reference]
32161-06-1(CAS DataBase Reference) | [NIST Chemistry Reference]
1-Acetyl-4-piperidone(32161-06-1) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H315-H319-H335 | [Precautionary statements ]
P261-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
10 | [HS Code ]
29333990 | [Storage Class]
10 - Combustible liquids |
| Hazard Information | Back Directory | [Chemical Properties]
clear orange oily liquid | [Uses]
1-Acetyl-4-piperidone is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs, and manufacture of fentanyl. | [Purification Methods]
Purify it by fractional distillaton through a short Vigreux column (15mm, p 11). The 2,4-dinitrophenylhydrazone has m 212-213o (from EtOH). It is freely soluble in H2O but insoluble in Et2O. [McElvain & McMahon J Am Chem Soc 71 901 1949, Beilstein 21/6 V 246.] |
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