ChemicalBook--->CAS DataBase List--->41661-47-6

41661-47-6

Request For Quotation
41661-47-6 Structure

41661-47-6 Structure
IdentificationMore
[Name]

4-Piperidinone
[CAS]

41661-47-6
[Synonyms]

4-PIPERIDONE
AKOS BBS-00004234
1-((6-chloro-2,3-dihydro-2-(4-methoxyphenyl)-3-oxo-1h-isoindol-1-yl)acetyl)-4-piperidinon
1-yl)acetyl)-
3-dihydro-2-(4-methoxyphenyl)-3-oxo-1h-isoindol-1-yl)acetyl)-1-((6-chloro-
4-Oxopiperidine
4-piperidinone
Piperidin-4-one
γ-Piperidinone
γ-Piperidone
4-Piperidinon
1’
-t-Butoxycarbonyl-5-hydroxy-spiro[chroman-2,4’
7-Methoxy-spiro[chroman-2,3’
[EINECS(EC#)]

255-481-1
[Molecular Formula]

C5H9NO
[MDL Number]

MFCD00955709
[Molecular Weight]

99.13
[MOL File]

41661-47-6.mol
Chemical PropertiesBack Directory
[Boiling point ]

175.1±15.0 °C(Predicted)
[density ]

1.001±0.06 g/cm3(Predicted)
[form ]

solid
[pka]

8.95±0.20(Predicted)
[color ]

yellow
[CAS DataBase Reference]

41661-47-6(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P271-P261-P280
[Risk Statements ]

R11:Highly Flammable.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
[Safety Statements ]

S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
[RIDADR ]

1993
[HazardClass ]

IRRITANT
[HS Code ]

2914390090
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Hydrochloric acid-->Toluene-->Potassium carbonate-->Sodium hydride-->Ethyl acrylate-->Benzamide
[Preparation Products]

1,4-Dioxa-8-azaspiro[4.5]decane-->Methyl 1-benzyl-4-oxo-3-piperidine-carboxylate hydrochloride-->1-Cbz-4-Piperidone-->(1-Benzylpiperidin-4-ylidene)acetic acid ethyl ester-->methyl 4-oxopiperidine-1-carboxylate-->Methyl 4-hydroxypiperidine-1-carboxyl-->tert-Butyl 3-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate-->1-Propyl-4-piperidone-->N-Acetyl-4-piperidone-->1-(4-Bromophenylsulfonyl)piperidin-4-one
Hazard InformationBack Directory
[Description]

4-Piperidinone is a derivative of piperidine with the molecular formula C5H9NO. 4-Piperidone is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs.
Piperidones are a class of chemical compounds sharing the piperidone skeleton. A classic named reaction for the synthesis of piperidones is the Petrenko-Kritschenko piperidone synthesis which involves combining an alkyl-1,3-acetonedicarboxylate with benzaldehyde and an amine. This multicomponent reaction is related to the Hantzsch pyridine synthesis.
[Uses]

4-Piperidone monohydrate hydrochloride was used in the generation of compound libraries based on sub-reactions of an Ugi multicomponent reaction (MCR).
[Synthesis]

A method for synthesizing an intermediate 4-piperidone, comprising the following steps:

(1) adding β-alanine methyl ester to ethanol, placing it in a reaction kettle, adding ethylene, mixing it well, lowering the temperature to 0°C, adding PS-AlC

Spectrum DetailBack Directory
[Spectrum Detail]

4-Piperidinone(41661-47-6)MS
4-Piperidinone(41661-47-6)IR1
4-Piperidinone(41661-47-6)IR2
41661-47-6 suppliers list
Tags:41661-47-6 Related Product Information
1445-73-4 548-73-2 36768-62-4 29976-53-2 52-86-8 2403-88-5 32161-06-1 826-36-8 1454-53-1 3612-20-2 40064-34-4 915-30-0 39742-60-4 5932-53-6 33973-59-0 79099-07-3 50-35-1 19099-93-5