| Identification | Back Directory | [Name]
4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE | [CAS]
3223-07-2 | [Synonyms]
EVOMELA
MELPHALAN HCL
MELPHALAN HYDROCHLORIDE
l-sarcolysinehydrochloride
Melphalan hydrochloride CRS
Melphalan for system suitability
phenylalaninemustardhydrochloride
alaninenitrogenmustardhydrochloride
l-phenylalaninemustardhydrochloride
4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE
4-[Bis(2-chloroethyl)amino]-L-phenylalanine hydrochloride
3-(p-(bis(2-chloroethyl)amino)phenyl)-l-alaninhydrochloride
4-(bis(2-chloroethyl)amino)-l-phenylalaninmonohydrochloride
(S)-3-[4-[Bis(2-chloroethyl)amino]phenyl]alanine hydrochloride
4-[Bis(2-chloroethyl)amino]-L-phenylalanine hydrochloride (1:1)
l-3-(p-(bis(2-chloroethyl)amino)phenyl)alaninemonohydrochloride
Phenylalanine, 4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1)
3-(p-(bis(2-chloroethyl)amino)phenyl)-,monohydrochloride,l-alanin
4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE USP/EP/BP
Melphalan Hydrochloride (100 mg) (International Restricted Sales Item)
2-AMINO-3-(4-(BIS(2-CHLOROETHYL)AMINO)PHENYL)PROPANOIC ACID HYDROCHLORIDE (MELPHALAN HYDROCHLORIDE) | [EINECS(EC#)]
643-091-8 | [Molecular Formula]
C13H19Cl3N2O2 | [MDL Number]
MFCD01674304 | [MOL File]
3223-07-2.mol | [Molecular Weight]
341.66 |
| Chemical Properties | Back Directory | [Melting point ]
175-178 °C | [storage temp. ]
2-8°C | [solubility ]
Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
Moisture Sensitive | [Major Application]
pharmaceutical (small molecule) | [InChI]
InChI=1S/C13H18Cl2N2O2.ClH/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19;/h1-4,12H,5-9,16H2,(H,18,19);1H | [InChIKey]
OUUYBRCCFUEMLH-UHFFFAOYSA-N | [SMILES]
C1(=CC=C(CC(N)C(=O)O)C=C1)N(CCCl)CCCl.Cl |
| Hazard Information | Back Directory | [Uses]
Melphalan Hydrochloride is used in combined intravitreal chemotherapy with topotecan hydrochloride for viable vitreous seeding from retinoblastoma. Also, it is an anti-cancer chemotherapy drug. | [Safety Profile]
Deadly poison by intravenousroute. Human systemic effects by ingestion: nausea andvomiting. Questionable carcinogen with experimentalcarcinogenic data. When heated to decomposition it emitsvery toxic fumes of Cl-, NOx, and HCl. |
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