ChemicalBook--->CAS DataBase List--->32399-08-9

32399-08-9

32399-08-9 Structure

32399-08-9 Structure
IdentificationBack Directory
[Name]

2-Methylaminopyridine-3-carbaldehyde
[CAS]

32399-08-9
[Synonyms]

2-(Methylamino)nicotinaldehyde
2-Methylaminopyridine-3-carbaldehyde
2-Methylamino-3-pyridinecarboxaldehyde
3-Pyridinecarboxaldehyde, 2-(methylamino)-
2-(methylamino)nicotinaldehyde(SALTDATA: HCl)
[Molecular Formula]

C7H8N2O
[MDL Number]

MFCD05863669
[MOL File]

32399-08-9.mol
[Molecular Weight]

136.15
Chemical PropertiesBack Directory
[Boiling point ]

281.7±25.0 °C(Predicted)
[density ]

1.196±0.06 g/cm3(Predicted)
[storage temp. ]

under inert gas (nitrogen or Argon) at 2-8°C
[pka]

5.00±0.10(Predicted)
[Appearance]

Light yellow to brown Liquid
Questions And AnswerBack Directory
[Uses]

2-Methylamino-3-pyridinecarboxaldehyde is a pyridine derivative that can be used for the structural modification and derivatization of pyridine-containing drug molecules and bioactive molecules.
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P280-P305+P351+P338
[HazardClass ]

IRRITANT
[HS Code ]

2933399990
Spectrum DetailBack Directory
[Spectrum Detail]

2-Methylaminopyridine-3-carbaldehyde(32399-08-9)1HNMR
Hazard InformationBack Directory
[Synthesis]

2-(Methylamino)pyridine-3-methanol

32399-12-5

2-Methylaminopyridine-3-carbaldehyde

32399-08-9

Preparation of 2-(Methylamino)nicotinaldehyde: 9.10 g (66.0 mmol) of 2-(methylamino)-3-pyridinemethanol was dissolved in 70 mL of chloroform and 17.4 g (200 mmol) of manganese dioxide was added. The reaction mixture was stirred at 60 °C overnight. Upon completion of the reaction, the mixture was filtered and the filtrate was concentrated to give 8.66 g (yield: 96%) of 2-(methylamino)nicotinaldehyde as an orange solid.NMR data (CDCl3/TMS, δ, ppm): 3.10 (3H, d), 6.62-6.66 (1H, m), 7.74 (1H, d), 8.36 (1H, d), 9.80 (1H, s).

[References]

[1] Patent: US2011/287937, 2011, A1. Location in patent: Page/Page column 69
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