| Identification | Back Directory | [Name]
Nicarbazin | [CAS]
330-95-0 | [Synonyms]
mk75
nicarb
nicoxin
nirazin
Nicarzin
nicrazin
nicrazine
nicarbazi
NICARBAZIN
NICARBAZINE
NICARBAZINUM
n,n’-bis(4-nitro
Nicarbazine Pure
1,3-bis(4-nitrophenyl)urea-4,6-dimethylpyrimidin-2-ol (1:1)
carbanilide,4,4’-dinitro-,compd.with4,6-dimethyl-2-pyrimidinol(1:1)
n,n’-bis(4-nitrophenyl)ureacompd.with4,6-dimethyl-2-pyrimidinol(1:1)
N,N'-BIS(4-NITROPHENYL)UREA COMPOUND WITH 4,6-DIMETHYL-2-PYRIMIDINONE
urea,n,n’-bis(4-nitrophenyl)-,compd.with4,6-dimethyl-2(1h)-pyrimidinone(
Urea, N,N-bis(4-nitrophenyl)-, compd. with 4,6-dimethyl-2(1H)-pyrimidinone (1:1)
Nicarbazin,N,N′-bis(4-Nitrophenyl)urea compound with 4,6-dimethyl-2-pyrimidinone | [EINECS(EC#)]
206-359-1 | [Molecular Formula]
C19H18N6O6 | [MDL Number]
MFCD00867204 | [MOL File]
330-95-0.mol | [Molecular Weight]
426.38 |
| Chemical Properties | Back Directory | [Definition]
Equimolar complex of 4,4′-dinitrocarbanilide and 2-hydroxy-4,6-dimethylpyrimidine | [Appearance]
Forms crystals.Insoluble in water | [Melting point ]
265-267 °C | [Boiling point ]
541.86°C (rough estimate) | [density ]
1.4663 (rough estimate) | [refractive index ]
1.6000 (estimate) | [storage temp. ]
0-6°C | [solubility ]
DMSO: soluble0.5mg/mL | [form ]
neat | [color ]
Yellow to Dark Yellow | [Major Application]
clinical testing | [InChI]
InChI=1S/C13H10N4O5.C6H8N2O/c18-13(14-9-1-5-11(6-2-9)16(19)20)15-10-3-7-12(8-4-10)17(21)22;1-4-3-5(2)8-6(9)7-4/h1-8H,(H2,14,15,18);3H,1-2H3,(H,7,8,9) | [InChIKey]
UKHWDRMMMYWSFL-UHFFFAOYSA-N | [SMILES]
C1(=CC=C([N+]([O-])=O)C=C1)NC(NC1=CC=C([N+]([O-])=O)C=C1)=O.C1(C)=NC(=NC(C)=C1)O | [Uses]
Coccidiostat. | [EPA Substance Registry System]
Urea, N,N'-bis(4-nitrophenyl)-, compd. with 4,6-dimethyl-2(1H)-pyrimidinone (1:1)(330-95-0) |
| Hazard Information | Back Directory | [Chemical Properties]
Forms crystals.Insoluble in water | [Biochem/physiol Actions]
Nicarbazin, an effective anticoccidial, is also a wide-spectrum anti-parasitic drug. It affects avian reproduction by reducing egg production, egg weight, and egg hatchability. The mechanism of action of Nicarbazin is unknown. | [Mode of action]
Nicarbazin interferes with the formation of the vitelline membrane, separating the egg yolk and egg white. The exact mode of action is unknown, although it is thought nicarbazin interferes with cholesterol metabolism in the formation of the membrane. Eggs from treated birds are described as mottled in appearance, reflecting a porous vitelline membrane. The effect on hatchability is a function of time and dose and the effect is reversible. |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
NCE Biomedical Co.,Ltd.
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| Telephone: |
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15748/0_EN.htm |
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