| Identification | More | [Name]
Ethopabate | [CAS]
59-06-3 | [Synonyms]
4-ACETYLAMINO-2-ETHOXY-BENZOIC ACID METHYL ESTER
ETHOPABATE
METHYL 4-ACETAMIDO-2-ETHOXYBENZOATE
Ethopabate, Vetranal
ETHOPABATE (4-ACETYLAMINO-2-ETHOXY-BENZOIC ACID METHYL ESTER)
4-Acetamido-2-ethoxybenzoic acid, methyl ester
Ethopatate
Ethytpatate
METHYL 5-ACETAMIDO-2-ETHOXYBENZOATE (ETHOPABATE)
Ethopabate, Methyl 4-acetamido-2-ethoxybenzoate
Isovaleraldehvde
Benzoic acid, 4-(acetylamino)-2-ethoxy-, methyl ester
Ethyl pabate
Methyl 4-(acetylamino)-2-ethoxybenzoate
4-Acetylamino-2-ethoxybenzoic acid methyl | [EINECS(EC#)]
200-414-3 | [Molecular Formula]
C12H15NO4 | [MDL Number]
MFCD00075809 | [Molecular Weight]
237.25 | [MOL File]
59-06-3.mol |
| Chemical Properties | Back Directory | [Melting point ]
148-151 °C
| [Boiling point ]
426.1±35.0 °C(Predicted) | [density ]
1.180±0.06 g/cm3(Predicted) | [storage temp. ]
0-6°C | [solubility ]
DMSO: 50 mg/mL (210.75 mM) | [form ]
A solid | [pka]
14.12±0.70(Predicted) | [color ]
White to off-white | [Merck ]
13,3781 | [Major Application]
forensics and toxicology
pharmaceutical (small molecule) | [InChI]
InChI=1S/C12H15NO4/c1-4-17-11-7-9(13-8(2)14)5-6-10(11)12(15)16-3/h5-7H,4H2,1-3H3,(H,13,14) | [InChIKey]
GOVWOKSKFSBNGD-UHFFFAOYSA-N | [SMILES]
C(OC)(=O)C1=CC=C(NC(C)=O)C=C1OCC | [CAS DataBase Reference]
59-06-3(CAS DataBase Reference) | [EPA Substance Registry System]
59-06-3(EPA Substance) |
| Hazard Information | Back Directory | [Description]
Ethopabate is a veterinary drug belonging to the class of antibiotics which contains an arylamide with a phenyl ring, a monocyclic aromatic hydrocarbon, and is a very safe drug used for the prophylaxis and treatment of coccidiosis in chickens. It has anticoccidial activity, especially against the intestinal form, and lacks activity against E. tenella of the cecum worm. The drug is a competitor of PABA, which is absorbed by the parasite and interferes with folate synthesis. It has good activity against E. acervulina and some strains of E. maxima and E. brunette. It is used only in combination with amprolium, first at a concentration of 4 ppm and later at a concentration of 40 ppm.This drug reaches peak activity on day 4 of the cycle. | [Chemical Properties]
White to Off-White Solid | [Uses]
A supplementary drug that improves the coccidiostatic effect of nicarbazin and amprolium in order to cure coccidiosis in chickens. | [Uses]
antidepressant | [Definition]
ChEBI: Ethopabate is an amidobenzoic acid. | [Clinical Use]
Ethopabate is only a narrow anticoccidial spectrum drug against Eimeria acervulina. It has no or only slight activity against E. maxima, E. necatrix, E. tenella or E. brunetti. Today, ethopabate is applied only in combination with amprolium and sulfonamide. | [Molecular Interactions]
Ethopabate is a 2-substituted PABA derivative (=4-acetamido-2-ethoxybenzoic acid methylester) and functions as a prodrug. Its activity becomes potentiated by pyrimethamine and antagonised by the simultaneous administration of PABA. Thus, the mode of action of ethopabate is similar to that of sulfonamides or sulfones. | [storage]
Store at -20°C |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Telephone: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
|