| Identification | More | [Name]
D-Pyrrolidine-2-carboxylic acid | [CAS]
344-25-2 | [Synonyms]
D-2-PYRROLIDINECARBOXYLIC ACID
D-PRO
D(+)-PROLINE
D-PROLINE
D-PYRROLIDINE-2-CARBOXYLIC ACID
H-D-PRO-OH
H-D-PYRD(2)-OH
(R)-(+)-PROLINE
(R)-PYRROLIDINE-2-CARBOXYLIC ACID
(2R)-Pyrrolidine-2-carboxylic acid
D-PROLINE, 99+% (98% EE/GLC)
D-Proline,99%
H-D-PRO-OH UPS24 (IN BULK QUANTITY)
D-(+)-Prolin
Proline
Glycinate Fumasuan Salt
D-(+)-PROLINE ((R)-(+)-PROLINE)
D-PROLINE extrapure | [EINECS(EC#)]
206-452-7 | [Molecular Formula]
C5H9NO2 | [MDL Number]
MFCD00064317 | [Molecular Weight]
115.13 | [MOL File]
344-25-2.mol |
| Chemical Properties | Back Directory | [Appearance]
White to off-white powder | [Melting point ]
223 °C (dec.) (lit.) | [alpha ]
84.75 º (c=4, H2O) | [Boiling point ]
215.41°C (rough estimate) | [density ]
1.36 | [refractive index ]
85 ° (C=4, H2O) | [storage temp. ]
Store at RT. | [solubility ]
Methanol (Slightly), Water (Sparingly) | [form ]
Powder | [pka]
1.952(at 25℃) | [color ]
White to yellow to pale brown | [Optical Rotation]
[α]22/D +85.0°, c = 4 in H2O | [Water Solubility ]
soluble >1000 g/L (20 ºC) | [Sensitive ]
Hygroscopic | [Detection Methods]
Rotation,T,NMR | [BRN ]
80811 | [InChI]
1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1 | [InChIKey]
ONIBWKKTOPOVIA-SCSAIBSYSA-N | [SMILES]
OC(=O)[C@H]1CCCN1 | [LogP]
-0.060 (est) | [Uses]
proline is a skin-conditioning agent. An amino acid found in the collagen molecule. | [CAS DataBase Reference]
344-25-2(CAS DataBase Reference) | [EPA Substance Registry System]
344-25-2(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P271-P280 | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
3-10 | [Hazard Note ]
Irritant | [TSCA ]
Yes | [REACH Registrations]
Active | [HS Code ]
29339900 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
White to off-white powder | [Occurrence]
D-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva. These amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity. | [Definition]
ChEBI: The D-enantiomer of proline. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 71, p. 2818, 1949 DOI: 10.1021/ja01176a065
Tetrahedron Letters, 28, p. 6469, 1987 DOI: 10.1016/S0040-4039(00)96890-4 | [reaction suitability]
reaction type: solution phase peptide synthesis | [Synthesis]
D-amino acids are an important class of chiral reagents and chiral intermediates. Currently, most of the D-amino acids are produced by synthesizing the racemates and then splitting them to obtain the optical isomers. The asymmetric conversion method, u | [storage]
Store at -20°C |
|
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Shanghai YuLue Chemical Co., Ltd. Gold
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021-60345187 13671753212 |
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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https://www.jkchemical.com |
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Alfa Aesar
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400-6106006 |
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http://chemicals.thermofisher.cn |
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Energy Chemical
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400-0056266 |
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www.energy-chemical.com |
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