| Identification | More | [Name]
5-Fluorosalicylic acid | [CAS]
345-16-4 | [Synonyms]
2-HYDROXY-5-FLUOROBENZOIC ACID
5-FLUORO-2-HYDROBENZOIC ACID
5-fluoro-2-hydroxybenzoic
5-FLUORO-2-HYDROXYBENZOIC ACID
5-FLUOROSALICYLIC ACID
BUTTPARK 34\01-09
RARECHEM AL BE 0856
5-Fluoro-2-Hydroxy Benzoic Acid 5-Fluoro Sallicylic Acid 2-Hydroxy-5-Fluoro Benzoic Acid
5-Fluorosalicylicacid,98+%
5-Fluorosalicylic
5-Fluoro-2-hydroxybenzoic acid 97%
5-Fluoro-2-hydroxybenzoicacid97%
5-FluoroSallicylicAcid
5-FLUOROSALICYLIC ACID 97% | [EINECS(EC#)]
206-455-3 | [Molecular Formula]
C7H5FO3 | [MDL Number]
MFCD00002456 | [Molecular Weight]
156.11 | [MOL File]
345-16-4.mol |
| Chemical Properties | Back Directory | [Appearance]
light yellow powder | [Melting point ]
177-179 °C (lit.) | [Boiling point ]
307.4±27.0 °C(Predicted) | [density ]
1.3290 (estimate) | [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
powder to crystal | [pka]
2.68±0.10(Predicted) | [color ]
light brown
| [Water Solubility ]
Slightly soluble in water. | [BRN ]
2209120 | [InChI]
InChI=1S/C7H5FO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,(H,10,11) | [InChIKey]
JWPRICQKUNODPZ-UHFFFAOYSA-N | [SMILES]
C(O)(=O)C1=CC(F)=CC=C1O | [CAS DataBase Reference]
345-16-4(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzoic acid, 5-fluoro-2-hydroxy-(345-16-4) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R37/38:Irritating to respiratory system and skin .
R36:Irritating to the eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29182900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Description]
5-Fluorosalicylic acid (FSA) is prepared by reacting p-fluorophenol with carbon dioxide under heated and pressurised conditions in the presence of an alkaline catalyst. It is an excellent chelating agent which forms highly fluorescent ternary complexes with terbium ions (Tb³⁺), and is utilised in immunological assays. FSA also serves as a building block for active pharmaceutical ingredients (APIs), such as fluorinated deferoxamine used in the treatment of chronic iron overload. | [Chemical Properties]
light yellow powder | [Uses]
5-Fluorosalicylic acid was used as internal standard in the quantification of salicylic acid. | [Synthesis Reference(s)]
Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8 |
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