| Identification | Back Directory | [Name]
1,2-Dihydrobenzocyclobutene-1-carboxylic acid methyl ester | [CAS]
35095-07-9 | [Synonyms]
Methyl bicyclo[4.2.0]octa-1,3
Benzocyclobutene-1-carboxylic acid methyl ester
Methyl bicyclo[4.2.0]octa-1,3,5-triene-7-carboxylate
Methyl bicyclo[4.2.0]octa-1,3,5,7-tetraene-7-carboxylate
1,2-Dihydrobenzocyclobutene-1-carboxylic acid methyl ester
Bicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid methyl ester | [EINECS(EC#)]
233-305-4 | [Molecular Formula]
C10H10O2 | [MDL Number]
MFCD21765233 | [MOL File]
35095-07-9.mol | [Molecular Weight]
162.19 |
| Chemical Properties | Back Directory | [Boiling point ]
68℃ (25 Torr) | [density ]
1.171±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
liquid | [color ]
colourless | [InChI]
InChI=1S/C10H10O2/c1-12-10(11)9-6-7-4-2-3-5-8(7)9/h2-5,9H,6H2,1H3 | [InChIKey]
XWGYSWFRKUQSLL-UHFFFAOYSA-N | [SMILES]
C12C(C(C(OC)=O)C1)=CC=CC=2 | [LogP]
1.49930 |
| Hazard Information | Back Directory | [Chemical Properties]
colourless liquid | [Uses]
1,2-Dihydrobenzocyclobutene-1-carboxylic acid methyl ester is a substituted benzocyclobutene (BCB) compound. It is used in the preparation of high-performance thermosetting polymers (BCB resins) and is widely used in the microelectronics sector. | [Synthesis]
GENERAL METHOD: A mixture of 2-(trimethylmethylsilyl)phenyl trifluoromethanesulfonate (3 mmol, 2.0 eq.), compound (CAS:292638-85-8, 1.0 eq.) and anhydrous cesium fluoride (6.0 eq.) was dissolved in dry acetonitrile (15 mL). The reaction mixture was stirred at room temperature for 12 hours. Upon completion of the reaction, 20 mL of water was added to the mixture and extracted with dichloromethane (3 x 20 mL). The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: petroleum ether) to afford the target product methyl benzocyclobutene-1-carboxylate (3c-6c). Compound 5c: pale yellow oil.1H NMR (400 MHz, CDCl3): δ 7.26-7.24 (m, 2H), 7.18 (d, 1H, J = 4 Hz), 7.11 (d, 1H, J = 4 Hz), 4.32 (t, 1H, J = 4 Hz), 3.73 (d, 3H, J = 8 Hz), 3.48 (d, 2H, J = 4 Hz). These data are in good agreement with literature values [14]. | [References]
[1] Chinese Chemical Letters, 2014, vol. 25, # 12, p. 1535 - 1539 |
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BePharm Ltd
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| Telephone: |
400-685-9117 |
| Website: |
www.bepharm.com |
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