ChemicalBook--->CAS DataBase List--->35475-03-7

35475-03-7

35475-03-7 Structure

35475-03-7 Structure
IdentificationBack Directory
[Name]

Methyl-5-chlorothiophene-2-carboxylate
[CAS]

35475-03-7
[Synonyms]

Rivaroxaban Impurity 149
Rivaroxaban Impurity 110
Methyl 2-chloro-5-thiophenecarboxylate
Methyl 5-chloro-2-thiophenecarboxylate
Methyl-5-chlorothiophene-2-carboxylate
5-chloro-2-Thiophenecarboxylic acid methyl ester
5-Chlorothiophene-2-carboxylic Acid Methyl Ester
5-chloro-2-Thiophene carbocylic acid methyl ester
2-Thiophenecarboxylic acid, 5-chloro-, Methyl ester
Methyl 2-chloro-5-thiophenecarboxylate (Rivaroxaban Impurity)
[Molecular Formula]

C6H5ClO2S
[MDL Number]

MFCD06203698
[MOL File]

35475-03-7.mol
[Molecular Weight]

177
Chemical PropertiesBack Directory
[Melting point ]

16.5-18℃
[Boiling point ]

95-97℃ (7 Torr)
[density ]

1.371±0.06 g/cm3(Predicted)
[refractive index ]

1.56
[storage temp. ]

under inert gas (nitrogen or Argon) at 2–8 °C
[solubility ]

Chloroform (Slightly)
[form ]

Oil
[color ]

Colourless
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H335-H319
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501
[HS Code ]

2934999090
Spectrum DetailBack Directory
[Spectrum Detail]

Methyl-5-chlorothiophene-2-carboxylate(35475-03-7)1HNMR
Hazard InformationBack Directory
[References]

[1] Patent: WO2008/98104, 2008, A1. Location in patent: Page/Page column 109; 188
[2] Organic Letters, 2017, vol. 19, # 21, p. 5976 - 5979
[3] Patent: CN107903208, 2018, A. Location in patent: Paragraph 0137; 0138
[4] Patent: EP1688420, 2006, A1. Location in patent: Page/Page column 122
[5] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 22, p. 5717 - 5729
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