| Identification | Back Directory | [Name]
Methyl-5-chlorothiophene-2-carboxylate | [CAS]
35475-03-7 | [Synonyms]
Rivaroxaban Impurity 149
Rivaroxaban Impurity 110
Methyl 2-chloro-5-thiophenecarboxylate
Methyl 5-chloro-2-thiophenecarboxylate
Methyl-5-chlorothiophene-2-carboxylate
5-chloro-2-Thiophenecarboxylic acid methyl ester
5-Chlorothiophene-2-carboxylic Acid Methyl Ester
5-chloro-2-Thiophene carbocylic acid methyl ester
2-Thiophenecarboxylic acid, 5-chloro-, Methyl ester
Methyl 2-chloro-5-thiophenecarboxylate (Rivaroxaban Impurity) | [Molecular Formula]
C6H5ClO2S | [MDL Number]
MFCD06203698 | [MOL File]
35475-03-7.mol | [Molecular Weight]
177 |
| Chemical Properties | Back Directory | [Melting point ]
16.5-18℃ | [Boiling point ]
95-97℃ (7 Torr) | [density ]
1.371±0.06 g/cm3(Predicted) | [refractive index ]
1.56 | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [solubility ]
Chloroform (Slightly) | [form ]
Oil | [color ]
Colourless |
| Hazard Information | Back Directory | [References]
[1] Patent: WO2008/98104, 2008, A1. Location in patent: Page/Page column 109; 188
[2] Organic Letters, 2017, vol. 19, # 21, p. 5976 - 5979
[3] Patent: CN107903208, 2018, A. Location in patent: Paragraph 0137; 0138
[4] Patent: EP1688420, 2006, A1. Location in patent: Page/Page column 122
[5] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 22, p. 5717 - 5729 |
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