| Identification | More | [Name]
Dimethyldioctadecylammonium bromide | [CAS]
3700-67-2 | [Synonyms]
18:0 DDAB
DDA
DDAB
DIMETHYL DI-N-OCTADECYLAMMONIUM BROMIDE
DIMETHYLDIOCTADECYLAMMONIUM BROMIDE
DIMETHYLDISTEARYLAMMONIUM BROMIDE
DISTEARYLDIMETHYLAMMONIUM BROMIDE
N,N-DIMETHYL-N,N-DISTEARYLAMMONIUM BROMIDE
n,n-dimethyl-n-octadecyl-1-octadecanaminiubromide
Dioctadecyl dimethyl ammonium bromide
Dimethyldioctadecylammonium bromide, 99+%
1-Octadecanaminium, N,N-dimethyl-N-octadecyl-, bromide
DIMETHYLDIOXTYLADECYLAMMONIUMBROMIDE
DDAB
DODAB
Bis(octadecyl)dimethylammonium bromide
Dioctadecanyldimethylammonium bromide
DODA(Br)
ERBU Adjuvant 100
Dimethylbis(octadecyl)aminium·bromide | [EINECS(EC#)]
223-037-6 | [Molecular Formula]
C38H80BrN | [MDL Number]
MFCD00041975 | [Molecular Weight]
630.95 | [MOL File]
3700-67-2.mol |
| Chemical Properties | Back Directory | [Appearance]
white powder | [Melting point ]
~160 °C | [density ]
1.047
| [refractive index ]
1.5260 (estimate) | [RTECS ]
RG0185984 | [storage temp. ]
-20°C | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly, Heated), Hexanes (Slightly, Heated) | [form ]
Granular Powder | [color ]
White | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [BRN ]
3580323 | [InChI]
InChI=1S/C38H80N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(3,4)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-38H2,1-4H3;1H/q+1;/p-1 | [InChIKey]
PSLWZOIUBRXAQW-UHFFFAOYSA-M | [SMILES]
C(CCCCCCCCCCCCCCCCC)[N+](C)(C)CCCCCCCCCCCCCCCCCC.[Br-] | [CAS DataBase Reference]
3700-67-2(CAS DataBase Reference) | [EPA Substance Registry System]
3700-67-2(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R43:May cause sensitization by skin contact. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [TSCA ]
Yes | [HazardClass ]
9 | [HS Code ]
29211990 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Description]
18:0 DDAB is a double-chained quaternary ammonium surfactant with a bromide counter ion. | [Chemical Properties]
white powder | [Uses]
Dimethyldioctadecylammonium bromide has been used in a study to assess the interaction of its monolayers with DNA using specular neutron reflection, surface pressure-area isotherms, and Brewster angle microscopy. It has also been used in a study to investigate new adjuvants for use in kill vaccines for bovine viral diarrhea virus (BVDV). | [General Description]
18:0 DDAB is cationic lipid and a quaternary ammonium salt. The hydrocarbon tails are saturated unlike the ionizable lipids. | [Biochem/physiol Actions]
18:0 DDAB is a surface-active molecule, used as an adjuvant to induce systemic immune response. It is non-toxic. | [Purification Methods]
Crystallise the bromide from acetone, then MeOH [Lukac J Am Chem Soc 106 4387 1984]. Also purify it by chromatography on alumina by washing with *C6H6 and eluting with Me2CO, evaporating and crystallising from MeCN [Swain & Kreevoy J Am Chem Soc 77 1126 1955]. [Beilstein 4 IV 829.] |
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